Q6FS55
Gene name |
KXD1 (CAGL0H03355g) |
Protein name |
Biogenesis of lysosome-related organelles complex 1 subunit KXD1 |
Names |
BLOC-1 subunit KXD1, KxDL homolog |
Species |
Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) (Yeast) (Torulopsis glabrata) |
KEGG Pathway |
cgr:CAGL0H03355g |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q6FS55
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q6FS55-F1 | Predicted | AlphaFoldDB |
No variants for Q6FS55
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q6FS55 | |||||
No associated diseases with Q6FS55
1 regional properties for Q6FS55
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | KxDL domain | 100 - 184 | IPR019371 |
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| BLOC-1 complex | A protein complex required for the biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes and platelet dense granules. Many of the protein subunits are conserved between mouse and human; the mouse complex contains the Pallidin, Muted, Cappuccino, Dysbindin, Snapin, BLOS1, BLOS2, AND BLOS3 proteins. |
| endosome | A vacuole to which materials ingested by endocytosis are delivered. |
| exodeoxyribonuclease VII complex | An enzyme complex that catalyzes exonucleolytic cleavage in either 5' to 3' or 3' to 5' direction to yield nucleoside 5'-phosphates; it prefers single-stranded DNA. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| exodeoxyribonuclease VII activity | Catalysis of the exonucleolytic cleavage in either 5' to 3' or 3' to 5' direction to yield 5'-phosphomononucleotides. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| DNA catabolic process | The cellular DNA metabolic process resulting in the breakdown of DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long unbranched macromolecule formed from one or two strands of linked deoxyribonucleotides, the 3'-phosphate group of each constituent deoxyribonucleotide being joined in 3',5'-phosphodiester linkage to the 5'-hydroxyl group of the deoxyribose moiety of the next one. |
| endosome organization | A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of endosomes. |
| regulation of protein localization | Any process that modulates the frequency, rate or extent of any process in which a protein is transported to, or maintained in, a specific location. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSDEIEDRPR | TRSRTPSVDT | QSYTINEEAH | HIITDSDSSS | SENEDGEGNE | TNSSDDSSES |
| 70 | 80 | 90 | 100 | 110 | 120 |
| GSVERFLDEI | VPTTSTSFIP | NDTPDPATLF | DITEYIFDSI | VQSTNACDFS | EAFALQAKTS |
| 130 | 140 | 150 | 160 | 170 | 180 |
| AVINSKSMEL | KNLIEQTKVR | LPELQAKFKN | GTQTLRTIRK | NLDNAKSRIQ | VMNDVLQTDY |
| 190 | 200 | ||||
| PIEFNQARDK | ILERTLDSDE | EVI |