Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q6FRZ3

Entry ID Method Resolution Chain Position Source
AF-Q6FRZ3-F1 Predicted AlphaFoldDB

No variants for Q6FRZ3

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q6FRZ3

No associated diseases with Q6FRZ3

8 regional properties for Q6FRZ3

Type Name Position InterPro Accession
domain Signal transduction response regulator, receiver domain 614 - 732 IPR001789
domain GAF domain 158 - 317 IPR003018
domain Histidine kinase/HSP90-like ATPase 455 - 589 IPR003594
domain Signal transduction histidine kinase, dimerisation/phosphoacceptor domain 341 - 408 IPR003661
domain Signal transduction histidine kinase-related protein, C-terminal 511 - 525 IPR004358-1
domain Signal transduction histidine kinase-related protein, C-terminal 529 - 539 IPR004358-2
domain Signal transduction histidine kinase-related protein, C-terminal 546 - 564 IPR004358-3
domain Histidine kinase domain 350 - 589 IPR005467

Functions

Description
EC Number
Subcellular Localization
  • Endoplasmic reticulum membrane ; Single-pass type I membrane protein
  • Golgi apparatus membrane ; Single-pass type I membrane protein
  • Recycles between endoplasmic reticulum and Golgi
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

4 GO annotations of cellular component

Name Definition
COPII-coated ER to Golgi transport vesicle A vesicle with a coat formed of the COPII coat complex proteins. The COPII coat complex is formed by the Sec23p/Sec24p and the Sec13p/Sec31p heterodimers. COPII-associated vesicles transport proteins from the rough endoplasmic reticulum to the Golgi apparatus (anterograde transport).
endoplasmic reticulum membrane The lipid bilayer surrounding the endoplasmic reticulum.
Golgi membrane The lipid bilayer surrounding any of the compartments of the Golgi apparatus.
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

2 GO annotations of biological process

Name Definition
endoplasmic reticulum to Golgi vesicle-mediated transport The directed movement of substances from the endoplasmic reticulum (ER) to the Golgi, mediated by COP II vesicles. Small COP II coated vesicles form from the ER and then fuse directly with the cis-Golgi. Larger structures are transported along microtubules to the cis-Golgi.
protein transport The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKFLLLLLLA PFISALRFDL KAESKPEQMC IRDFVSEGEL VVINIDTDGS LNDGNVLNLY
70 80 90 100 110 120
VHDSNGNEYR RLKNFVGEQR IAFTAPATTS FDVCFENTLD SNRGNRNAKR AIELDIESGS
130 140 150 160 170 180
QARDWNKISA TEKLRPIELE LRKIEELTDE IVDELNYLKN REERLRNTNE STNERVRNFS
190 200
VLVIIVLTSL GAWQVNYLKN YFKSKHII