Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q6FRU9

Entry ID Method Resolution Chain Position Source
AF-Q6FRU9-F1 Predicted AlphaFoldDB

No variants for Q6FRU9

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q6FRU9

No associated diseases with Q6FRU9

No regional properties for Q6FRU9

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q6FRU9

Functions

Description
EC Number
Subcellular Localization
  • Endoplasmic reticulum membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
integral component of endoplasmic reticulum membrane The component of the endoplasmic reticulum membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
Sec62/Sec63 complex A protein complex involved in the posttranslational targeting of proteins to the ER. In yeast, it is a tetrameric complex consisting of Sec62p, Sec63p, Sec71p and Sec72p.
translocon complex A protein complex that constitutes a specific site of protein translocation across the endoplasmic reticulum, which involves the signal recognition particle receptor. The complex contains a core heterotrimer of alpha, beta and gamma subunits, and may contain additional proteins.

1 GO annotations of molecular function

Name Definition
protein transmembrane transporter activity Enables the transfer of a protein from one side of a membrane to the other.

1 GO annotations of biological process

Name Definition
post-translational protein targeting to membrane, translocation The process in which a protein translocates through the ER membrane posttranslationally.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MDQSAVLAIA SFVRNRSELK ARKGLFQDKP TDFFRYKRFV RCLKSDAYKK KSLKQPDLYP
70 80 90 100 110 120
PLPEDEEKFA ELARGIFVEF IKNQLVVPGQ KLHSYECKEH GLKPSKDYPH LIMSTKATLD
130 140 150 160 170 180
DNEYYLWHYN PKTLTDYLIV FGVIGVILAF VCYPLWPASM RRGTYYLSLA AFGFLGVFFG
190 200 210 220 230 240
VAIIRLIVFL ISMLFIREKG GFWLFPNLFE DCGFFDSFKP LYGFGDKETY TYIKKMKKQK
250
KRQAKKEKLK KLKEKAN