Q6FPD4
Gene name |
ATG17 (CAGL0J04686g) |
Protein name |
Autophagy-related protein 17 |
Names |
|
Species |
Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) (Yeast) (Torulopsis glabrata) |
KEGG Pathway |
cgr:CAGL0J04686g |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q6FPD4
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q6FPD4-F1 | Predicted | AlphaFoldDB |
No variants for Q6FPD4
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q6FPD4 | |||||
No associated diseases with Q6FPD4
1 regional properties for Q6FPD4
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Sulfatase, N-terminal | 36 - 374 | IPR000917 |
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| Atg1/ULK1 kinase complex | A protein complex consisting of Atg1 (or Atg1 homologs e.g. ULK1, ULK2 in mammals) and Atg13 along with other proteins that regulate its function (e.g. Atg17 in yeast or RB1CC1(FIP200) in mammals). This complex has serine/threonine protein kinase activity and is involved in autophagosome formation. |
| phagophore assembly site membrane | A cellular membrane associated with the phagophore assembly site. |
| vacuole-isolation membrane contact site | An organelle membrane contact site formed at the junction of the vacuolar membrane and the isolation membrane or phagophore in response to starvation or other stresses, leading to the formation of the autophagosome. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| molecular adaptor activity | The binding activity of a molecule that brings together two or more molecules through a selective, non-covalent, often stoichiometric interaction, permitting those molecules to function in a coordinated way. |
| protein kinase activator activity | Binds to and increases the activity of a protein kinase, an enzyme which phosphorylates a protein. |
| SNARE binding | Binding to a SNARE (soluble N-ethylmaleimide-sensitive factor attached protein receptor) protein. |
7 GO annotations of biological process
| Name | Definition |
|---|---|
| autophagy of mitochondrion | The autophagic process in which mitochondria are delivered to a type of vacuole and degraded in response to changing cellular conditions. |
| autophagy of peroxisome | The process in which peroxisomes are delivered to a type of vacuole and degraded in response to changing nutrient conditions. |
| late nucleophagy | A type of nucleophagy, distinct from piecemeal microautophagy of the nucleus (PNM) where the nuclear material is delivered to the vacuole/lysosome for breakdown and recycling later than observed for PNM. |
| piecemeal microautophagy of the nucleus | Degradation of a cell nucleus by lysosomal microautophagy. |
| positive regulation of autophagosome assembly | Any process that activates or increases the frequency, rate or extent of autophagic vacuole assembly. |
| positive regulation of autophagosome size | Any process that increases autophagosome size. |
| protein localization to phagophore assembly site | Any process in which a protein is transported to, or maintained at, the phagophore assembly site (PAS). |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MPESLAERAR | STLLKAQVLC | REVESRIAEV | KDRLSQWEKN | RHTLRFLVSC | LEHQLGFLEQ |
| 70 | 80 | 90 | 100 | 110 | 120 |
| CALRQGIGRA | LIETEWSQVV | LVDLVNEMKL | WYDKIQLRLE | RLDQVENILV | ADNKHLSHYI |
| 130 | 140 | 150 | 160 | 170 | 180 |
| SQEQALVLKK | RLDEVPIIRP | QIENIQTQYD | TMCKRVRQKL | INKRLTEIKT | IFDSQFGDEL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| TETAELTEVK | PRDLDSIELE | LVDYINSLTD | HFDKCQALEK | GLFNDSNEYD | ELLKIVSADD |
| 250 | 260 | 270 | 280 | 290 | 300 |
| SQLDDIMKHL | LNTIDSTNHQ | IDKVYEILDI | KTKQKTILHG | KINELIANCT | KYSEYLAIFK |
| 310 | 320 | 330 | 340 | 350 | 360 |
| GIATSIEKFK | EGCMQDIQLT | KELYKFYDEF | ENSYNKLLQE | VQRRRALSQK | MLGIIKNCEN |
| 370 | 380 | 390 | 400 | ||
| ELKTLHDEDQ | KLRTHFLSEN | GAFLPETIWP | GEIDDLSPLY | ALDYHIKEI |