Q6FPC0
Gene name |
TIM54 (CAGL0J05016g) |
Protein name |
Mitochondrial import inner membrane translocase subunit TIM54 |
Names |
|
Species |
Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) (Yeast) (Torulopsis glabrata) |
KEGG Pathway |
cgr:CAGL0J05016g |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q6FPC0
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q6FPC0-F1 | Predicted | AlphaFoldDB |
No variants for Q6FPC0
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q6FPC0 | |||||
No associated diseases with Q6FPC0
No regional properties for Q6FPC0
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q6FPC0 | |||
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| TIM22 mitochondrial import inner membrane insertion complex | A multi-subunit complex embedded in the mitochondrial inner membrane that mediates the inner membrane insertion of multi-transmembrane spanning proteins that contain internal targeting elements. In yeast cells, TIM22 is a 300-kDa complex, consisting of four membrane integral subunits, Tim22, Tim54, Tim18 and Sdh3, and a peripheral chaperone complex consisting of the small TIM proteins, Tim9-Tim10-Tim12. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| protein transmembrane transporter activity | Enables the transfer of a protein from one side of a membrane to the other. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| protein insertion into mitochondrial inner membrane | The processes mediating the insertion of proteins into the mitochondrial inner membrane. Mitochondrial inner membrane proteins can get inserted from the cytosol, by crossing the outer membrane and being guided by an inner membrane translocase complex into their final destination in the inner membrane. Some proteins present in the intermembrane space can get inserted into the inner mitochondrial membrane. Finally, some proteins are inserted into the inner membrane from the matrix side of the membrane. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MNPALKALGL | GNFKLPSRNW | TIFWTVLAGS | LGGVGYDKYQ | QRQIISRYCD | EVKPLSLQHC |
| 70 | 80 | 90 | 100 | 110 | 120 |
| DVNKSPRKIT | VFIAPPPNDY | LETSLKIWRR | YIKPVLYYAG | LDYEVIEEDR | QGIIRSEVAS |
| 130 | 140 | 150 | 160 | 170 | 180 |
| RIRQLRRELL | EADNEQQGNS | GDSLLSIFKK | PHAKDPEEEQ | KFDPEQARQF | KADFDFRNVM |
| 190 | 200 | 210 | 220 | 230 | 240 |
| GIYTKVPKLD | TIVQTDSLVA | DPVLAGGVVC | VGRGAYKEYI | TGLHEGLLGP | LDPPEETTQE |
| 250 | 260 | 270 | 280 | 290 | 300 |
| VEMGSKLKSM | NDGDNVETTV | ETAVETMVET | TLESADKVEV | EGKDTENEEG | KDEPDEEKSR |
| 310 | 320 | 330 | 340 | 350 | 360 |
| VLKPYLLRTA | FHDTPIPPEV | EPVLEKDALL | KDPKTNVPSL | LHQPVLVIPV | PNLIGFLTIP |
| 370 | 380 | 390 | 400 | 410 | 420 |
| ERIYRFYQRR | FFVDEVCREA | SNLVKQEHIV | KYEPDKHINL | ALEEESDWPK | QWVKTGIEKN |
| 430 | 440 | 450 | |||
| SEWTQELVQD | QRVVSKMHVF | ELPKHTTKDT | KE |