Q6FMP4
Gene name |
TFB3 (CAGL0K06369g) |
Protein name |
RNA polymerase II transcription factor B subunit 3 |
Names |
RNA polymerase II transcription factor B 38 kDa subunit, RNA polymerase II transcription factor B p38 subunit |
Species |
Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) (Yeast) (Torulopsis glabrata) |
KEGG Pathway |
cgr:CAGL0K06369g |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q6FMP4
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q6FMP4-F1 | Predicted | AlphaFoldDB |
No variants for Q6FMP4
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q6FMP4 | |||||
No associated diseases with Q6FMP4
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| transcription factor TFIIK complex | A transcription factor complex that forms part of the holo TFIIH complex. In Saccharomyces/human, TFIIK contains Ccl1p/Cyclin H, Tfb3p/MAT1 and Kin28p/CDK7. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| cyclin-dependent protein serine/threonine kinase activator activity | Binds to and increases the activity of a cyclin-dependent protein serine/threonine kinase. |
| metal ion binding | Binding to a metal ion. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| nucleotide-excision repair | A DNA repair process in which a small region of the strand surrounding the damage is removed from the DNA helix as an oligonucleotide. The small gap left in the DNA helix is filled in by the sequential action of DNA polymerase and DNA ligase. Nucleotide excision repair recognizes a wide range of substrates, including damage caused by UV irradiation (pyrimidine dimers and 6-4 photoproducts) and chemicals (intrastrand cross-links and bulky adducts). |
| phosphorylation of RNA polymerase II C-terminal domain | The process of introducing a phosphate group on to an amino acid residue in the C-terminal domain of RNA polymerase II. Typically, this occurs during the transcription cycle and results in production of an RNA polymerase II enzyme where the carboxy-terminal domain (CTD) of the largest subunit is extensively phosphorylated, often referred to as hyperphosphorylated or the II(0) form. Specific types of phosphorylation within the CTD are usually associated with specific regions of genes, though there are exceptions. The phosphorylation state regulates the association of specific complexes such as the capping enzyme or 3'-RNA processing machinery to the elongating RNA polymerase complex. |
| transcription initiation at RNA polymerase II promoter | A transcription initiation process that takes place at a RNA polymerase II gene promoter. Messenger RNAs (mRNA) genes, as well as some non-coding RNAs, are transcribed by RNA polymerase II. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSSAVASKGM | NQGSEFDDNK | DMCPICKTDR | YLSPDVRFLV | NPECYHKICE | SCVDRIFSLG |
| 70 | 80 | 90 | 100 | 110 | 120 |
| PAPCPYKSCD | KILRKNKFKT | QIFDDVGVEK | EVDIRKRVFN | VFNKTLEDFD | NDLEAYNKYL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| EEVEDIVYKL | DNKIDVVETE | EKLRTYEELN | KQLIMNNMER | SKKDLENFEQ | RQQFEKEMRM |
| 190 | 200 | 210 | 220 | 230 | 240 |
| KKRMLERQIE | SEDKMNKEWA | KREIVNRLAS | STNADDVIEG | VKNTVKLKKS | SARRKLEEIN |
| 250 | 260 | 270 | 280 | 290 | 300 |
| RVLQNNPYSS | LMLSQGLSRK | EDNVPFTPFN | GDRDLDKRYT | IDQESYDDPF | IKDLENRKDY |
| 310 | 320 | ||||
| IASGFRSDFV | YDRMLTEAFM | GLGCVVAEEV |