Q6FML5

PR
Gene name
PRP5 (CAGL0K07029g)
Protein name
Pre-mRNA-processing ATP-dependent RNA helicase PRP5
Names
Species
Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) (Yeast) (Torulopsis glabrata)
KEGG Pathway
cgr:CAGL0K07029g
EC number
3.6.4.13: Acting on ATP; involved in cellular and subcellular movement
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-215 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q6FML5

Entry ID Method Resolution Chain Position Source
AF-Q6FML5-F1 Predicted AlphaFoldDB

No variants for Q6FML5

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q6FML5

No associated diseases with Q6FML5

5 regional properties for Q6FML5

Type Name Position InterPro Accession
conserved_site ATP-dependent RNA helicase DEAD-box, conserved site 408 - 416 IPR000629
domain Helicase, C-terminal 487 - 640 IPR001650
domain DEAD/DEAH box helicase domain 276 - 450 IPR011545
domain Helicase superfamily 1/2, ATP-binding domain 271 - 477 IPR014001
domain RNA helicase, DEAD-box type, Q motif 251 - 280 IPR014014

Functions

Description
EC Number 3.6.4.13 Acting on ATP; involved in cellular and subcellular movement
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

4 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP hydrolysis activity Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.
nucleic acid binding Binding to a nucleic acid.
RNA helicase activity Unwinding of an RNA helix, driven by ATP hydrolysis.

1 GO annotations of biological process

Name Definition
mRNA branch site recognition Recognition of the pre-mRNA branch site sequence by components of the assembling spliceosome.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTSIDKQKER LEKLARWKQK KSESKAVLNT QNVNTNSQSS NQNNVSDIEN KLEKVKAWKK
70 80 90 100 110 120
RKLEVKSDQQ TPPATQSEIN HTSSVRLEEN IQGIKRKKRQ KRVSNVFDEV KPINSTPTND
130 140 150 160 170 180
AQLSESDILE KVDLNTEDPL DSFFGNIETT EEFHFEVIDN KVNNDELLDE DNSKFDALQK
190 200 210 220 230 240
EQKKLAKAKK NKNKKLLTPV NFRNIDLDPI SKCLYNEPEE IKSYTEDEIA DLRLDLDNIK
250 260 270 280 290 300
IEGKDCPRPV TKWSQLGIPY DIIRFIKDVF SYKSLTPIQT QTIPAIMSGR DVIGISKTGS
310 320 330 340 350 360
GKTISYLLPM IRHVKAQKKL RNGETGPIAV IFAPTRELAV QINEEVQKLI SDLDISSICC
370 380 390 400 410 420
TGGSDLKKQI DKLKTGVEIA IATPGRFIDL LSLNGGNLVS TLRISFVVMD EADRLFDFGF
430 440 450 460 470 480
EPQIASVLRT VRPDRQCVLF SATFPSKVSN FASRFLDSPL QITVNAEGMV NERINQKFTI
490 500 510 520 530 540
CSDESDKFKE LLSLLKVFNS ETVDEKTIIF VSSQQICDII EKRLTDYSEK LYSIHAGRPY
550 560 570 580 590 600
NERRQNLELF KKTSNSILLC TEVMSRGLNV PEVSRVILYN SAKTFAQYVH STGRTARGTR
610 620 630 640 650 660
EGTSISLLLP NELSSAYILN KAMRDKDFSE CPVKEVKNLK QMAQKFEDGL KSGKYKLSTG
670 680 690 700 710 720
LGGKGLENMD NSKETSNNDL DEQLKHQDNI SISQEADLPD DFKFDTSVET VTNADGTIAT
730 740 750 760 770 780
VCKFVVNDLP QLVRWEMTKN TSISNMIRET GCSITLRGRY YPPSNVTNDN NTEPKLYLLI
790 800 810
EATDDKAVRH CVDLLKDNAR VGFMKATSES LRNTKY