Q6FLZ0
Gene name |
EPL1 (CAGL0K12386g) |
Protein name |
Enhancer of polycomb-like protein 1 |
Names |
|
Species |
Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) (Yeast) (Torulopsis glabrata) |
KEGG Pathway |
cgr:CAGL0K12386g |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q6FLZ0
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q6FLZ0-F1 | Predicted | AlphaFoldDB |
No variants for Q6FLZ0
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q6FLZ0 | |||||
No associated diseases with Q6FLZ0
No regional properties for Q6FLZ0
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q6FLZ0 | |||
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleosome | A complex comprised of DNA wound around a multisubunit core and associated proteins, which forms the primary packing unit of DNA into higher order structures. |
| Piccolo NuA4 histone acetyltransferase complex | A heterotrimeric H4/H2A histone acetyltransferase complex with a substrate preference of chromatin over free histones. It contains a subset of the proteins found in the larger NuA4 histone acetyltransferase complex; for example, the S. cerevisiae complex contains Esa1p, Yng2p, and Epl1p. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| histone acetyltransferase activity | Catalysis of the reaction: acetyl-CoA + histone = CoA + acetyl-histone. |
4 GO annotations of biological process
| Name | Definition |
|---|---|
| cell cycle | The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division. |
| DNA repair | The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway. |
| positive regulation of macroautophagy | Any process, such as recognition of nutrient depletion, that activates or increases the rate of macroautophagy to bring cytosolic macromolecules to the vacuole/lysosome for degradation. |
| regulation of transcription by RNA polymerase II | Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSSNGGSNTN | ERSVGPDSGS | LRSNSNLSSV | NGDGSDSGST | RFRHRKISVK | QRLRIHLPSD |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LKNLDKNEIQ | KRELLDVETG | VEKNEEKEVH | LHRILQKASV | LEHLNSKKDY | IPTPDASKTW |
| 130 | 140 | 150 | 160 | 170 | 180 |
| SDYDKFYSGK | FVETQAYVKF | SVTVEDCCGV | PYTLDEIDDD | FLENSLNKNS | DLKLNEDEFE |
| 190 | 200 | 210 | 220 | 230 | 240 |
| SLCSAFETAI | KERQPFLQMD | PETILTFDEV | KPTLLKVDFN | NMHLRSQLAQ | EVAAIHNPQT |
| 250 | 260 | 270 | 280 | 290 | 300 |
| ANSSSDGNGP | FTTVFDSSTT | ANVRPIPELI | EKYGKEVYEH | WSRRKIEAKG | AEIFPQLKFE |
| 310 | 320 | 330 | 340 | 350 | 360 |
| RPGEKEEVDP | YVCFRRRELR | HPRKTRRVDI | LNSQKLRILL | KELRHAKDMS | LLVAQREQIN |
| 370 | 380 | 390 | 400 | 410 | 420 |
| LQLIEDDLKI | LNKRKHVISI | KRKLDIKGED | EDLINHKRKR | PTIMTIEKKR | QQEEALAAAK |
| 430 | 440 | 450 | 460 | 470 | 480 |
| RAAEQEKAAA | AAKAAEAKNK | SKAQKKQNEQ | AAKVKSSKQK | NSSSQDLTKK | VTQEESQSEE |
| 490 | 500 | 510 | 520 | 530 | 540 |
| QQPAMSHVYV | KLPSSKIPDI | VLEDVEKLLQ | NKEKSARRFV | QERMARRKLE | DNDEFINLTD |
| 550 | 560 | 570 | 580 | 590 | 600 |
| DPHNPVFDLT | TLNCSEVPFS | PFSSIASSKL | KINKSFYLRD | LNDYLNGIAT | DLKVFNKDGE |
| 610 | 620 | 630 | 640 | 650 | 660 |
| KIEDNKTASG | NQNVRKTEVY | NPFDSGSELH | SREYPVKFRR | RFGRGNIEYL | DVKRKIDNFS |
| 670 | 680 | 690 | 700 | 710 | 720 |
| DTRFCEFIDF | KAIENQELEN | NGRNLDVYES | RADEFSRLLE | KWKFDSTNNE | YGLRFSDEPA |
| 730 | 740 | 750 | 760 | 770 | 780 |
| RLNQISNDTQ | VIRFGTMLGT | KSYEQLKEAT | IRYRKDYISR | IRQQKLNAQK | QQQILQQQQF |
| 790 | 800 | 810 | 820 | ||
| LQQQQENGSP | NNATMPINPI | NKSTLKQDVA | SNVLVGTQQK | S |