Q6FJS0

PR
Gene name
PFS2 (CAGL0M04081g)
Protein name
Polyadenylation factor subunit 2
Names
Species
Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) (Yeast) (Torulopsis glabrata)
KEGG Pathway
cgr:CAGL0M04081g
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-86 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q6FJS0

Entry ID Method Resolution Chain Position Source
AF-Q6FJS0-F1 Predicted AlphaFoldDB

No variants for Q6FJS0

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q6FJS0

No associated diseases with Q6FJS0

8 regional properties for Q6FJS0

Type Name Position InterPro Accession
repeat WD40 repeat 78 - 110 IPR001680-1
repeat WD40 repeat 113 - 152 IPR001680-2
repeat WD40 repeat 154 - 279 IPR001680-3
repeat WD40 repeat 283 - 322 IPR001680-4
repeat WD40 repeat 327 - 367 IPR001680-5
repeat G-protein beta WD-40 repeat 139 - 153 IPR020472-1
repeat G-protein beta WD-40 repeat 223 - 237 IPR020472-2
repeat G-protein beta WD-40 repeat 354 - 368 IPR020472-3

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
chromatin The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome.
mRNA cleavage and polyadenylation specificity factor complex A multisubunit complex that binds to the canonical AAUAAA hexamer and to U-rich upstream sequence elements on the pre-mRNA, thereby stimulating the otherwise weakly active and nonspecific polymerase to elongate efficiently RNAs containing a poly(A) signal.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

3 GO annotations of biological process

Name Definition
chromosome segregation The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. In eukaryotes, chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles.
mRNA polyadenylation The enzymatic addition of a sequence of 40-200 adenylyl residues at the 3' end of a eukaryotic mRNA primary transcript.
pre-mRNA cleavage required for polyadenylation The targeted, endonucleolytic cleavage of a pre-mRNA, required for polyadenylation of the 3' end. This cleavage is directed by binding sites near the 3' end of the mRNA and leaves a 3' hydoxyl end which then becomes a target for adenylation.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MDQSAAVEGV PQKKYLTLRR SVDVSSSYNR LYYLKKHGLS LPPIEPETSF TANIMPPDAY
70 80 90 100 110 120
KRNDRIVNLP TKFTHLSSNK VKHVIPAIQW SPEGRRLIVA TFSGEFSLWN GSSFTFETIM
130 140 150 160 170 180
QAHDTSVTTM KYSHAGDWMI SGDADGTIKI WQPNFNMVKE LDRIHTEGIR DVAFSNNDSK
190 200 210 220 230 240
FVTCSDDNIL KIWNFSNGQQ ERVLSGHHWD VRSCDWHPEL GLIVSGSKDN LVKLWDPRSG
250 260 270 280 290 300
QCVSTLLKFK HTVLKTRFQP TKGNLLAAIS KDKSCRVFDL RASMNELMCV RDEVDFMELE
310 320 330 340 350 360
WSTINESMFT VGCYDGSLKH FDLGQDTEKP IHIIPFAHEK CISAIAYNPV GHILATAAKD
370 380 390 400 410 420
RTIRFWTRAR PVDPNAFDDP TYNNKKMTGW FFGINNDINA VREKSEYGAA PPPASTAFPQ
430 440 450
QTQYNNNISR VPEIKEPTPT TDKEQRTSIL PGLSI