Q6FJJ8

PR
Gene name
MRH4 (CAGL0M05753g)
Protein name
ATP-dependent RNA helicase MRH4, mitochondrial
Names
Species
Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) (Yeast) (Torulopsis glabrata)
KEGG Pathway
cgr:CAGL0M05753g
EC number
3.6.4.13: Acting on ATP; involved in cellular and subcellular movement
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-112 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q6FJJ8

Entry ID Method Resolution Chain Position Source
AF-Q6FJJ8-F1 Predicted AlphaFoldDB

No variants for Q6FJJ8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q6FJJ8

No associated diseases with Q6FJJ8

3 regional properties for Q6FJJ8

Type Name Position InterPro Accession
domain Helicase, C-terminal 379 - 568 IPR001650
domain DEAD/DEAH box helicase domain 148 - 334 IPR011545
domain Helicase superfamily 1/2, ATP-binding domain 142 - 363 IPR014001

Functions

Description
EC Number 3.6.4.13 Acting on ATP; involved in cellular and subcellular movement
Subcellular Localization
  • Mitochondrion
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
mitochondrial matrix The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.

4 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP hydrolysis activity Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.
mitochondrial ribosomal large subunit rRNA binding Binding to a mitochondrial large ribosomal subunit RNA (LSU rRNA).
RNA helicase activity Unwinding of an RNA helix, driven by ATP hydrolysis.

2 GO annotations of biological process

Name Definition
mitochondrial large ribosomal subunit assembly The aggregation, arrangement and bonding together of a set of components to form a mitochondrial large ribosomal subunit.
RNA metabolic process The cellular chemical reactions and pathways involving RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MVSILAIRTF NPLGHFVSTQ CVRAYAINSV RAGSKSSSVR AGSKNDTTRA SSKKNKAGKS
70 80 90 100 110 120
KLQLSARFKQ NANKSQKADK FKSQKQFKYG LYGGLKENEN KFLETNANLV EKITEFEELK
130 140 150 160 170 180
LLPEVRKHVI NLIKKDSLNT TEEIHPSPIQ TIAIKRLSKN LMEPKLQVHA IAAETGSGKT
190 200 210 220 230 240
MAYCAPLLDY LKRQEIETPE KWESIKDKAI IRSVILVPTL ELVDQIYTTL TCIPDTLGIH
250 260 270 280 290 300
VHKWTTGVDY QQLLENLKSR TDILITTPSK LLSLQRVRMI SRADLILKRI EFVVLDEADT
310 320 330 340 350 360
LLDKSWLEDT HKALKAMSDV NHLVLCSATI PNEFDRTMTK MFPNAIPLTT PRLHKLPKGI
370 380 390 400 410 420
NFRIINAAVS PYKGSKIKAL AQTLYAIAYD GTDPGFEKRC IVFINEKKNV DNVVQKLRNE
430 440 450 460 470 480
YGHDVVGLTG DMEGRTRLEL IRPFISPPEK LTEQEKQIDK DLNDQETVNI SGSNISIGNI
490 500 510 520 530 540
ENSNKASNFI PKLRVLVTTD LLARGLNFKG VRNVILYDVP ITAIDLVHRA GRTARMRQSG
550 560
RVFMIIDKKT QSWAKAVPTI LKKNKALT