Q6FJ70

PR
Gene name
AKR1 (CAGL0M08712g)
Protein name
Palmitoyltransferase AKR1
Names
Ankyrin repeat-containing protein AKR1
Species
Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) (Yeast) (Torulopsis glabrata)
KEGG Pathway
cgr:CAGL0M08712g
EC number
2.3.1.225: Transferring groups other than amino-acyl groups
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

591-664 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q6FJ70

Entry ID Method Resolution Chain Position Source
AF-Q6FJ70-F1 Predicted AlphaFoldDB

No variants for Q6FJ70

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q6FJ70

No associated diseases with Q6FJ70

4 regional properties for Q6FJ70

Type Name Position InterPro Accession
domain Palmitoyltransferase, DHHC domain 450 - 581 IPR001594
repeat Ankyrin repeat 54 - 124 IPR002110-1
repeat Ankyrin repeat 126 - 158 IPR002110-2
repeat Ankyrin repeat 159 - 262 IPR002110-3

Functions

Description
EC Number 2.3.1.225 Transferring groups other than amino-acyl groups
Subcellular Localization
  • Early endosome membrane; Multi-pass membrane protein
  • Golgi apparatus membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
early endosome membrane The lipid bilayer surrounding an early endosome.
Golgi membrane The lipid bilayer surrounding any of the compartments of the Golgi apparatus.
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

2 GO annotations of molecular function

Name Definition
G-protein beta/gamma-subunit complex binding Binding to a complex of G-protein beta/gamma subunits.
protein-cysteine S-palmitoyltransferase activity Catalysis of the transfer of a palmitoyl (systematic name, hexadecanoyl) group to a sulfur atom on the cysteine of a protein molecule, in the reaction hexadecanoyl-CoA + L-cysteinyl-

4 GO annotations of biological process

Name Definition
negative regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion Any process that decreases the frequency, rate or extent of pheromone-dependent signal transduction during conjugation with cellular fusion, a signal transduction process resulting in the relay, amplification or dampening of a signal generated in response to pheromone exposure in organisms that undergo conjugation with cellular fusion.
protein palmitoylation The covalent attachment of a palmitoyl group to a protein.
protein targeting to membrane The process of directing proteins towards a membrane, usually using signals contained within the protein.
regulation of endocytosis Any process that modulates the frequency, rate or extent of endocytosis.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MEDNSEQASV SSQASMRPLV SDNGDREAGA GVEVNIANDN DTSVGVDGEN GNEDDDPILS
70 80 90 100 110 120
KYHNACQRGD LEVVREMIHG GQVNVSSDAD REGVTGLHWA AINNRLNVVD FLVREGANVE
130 140 150 160 170 180
SKAGALEATP LHWAARYGFV YVVDYLLQHG ASATTTDKQG FNLLHLSVNS SNIMLVVYVL
190 200 210 220 230 240
FFVVSKGIID IDYVDPKGRT ALLWAAYQGD SLTVAALIKF NASVKIADEG GFTPLHWGTV
250 260 270 280 290 300
KGQPHVLKYL IQDGADFFQK TNDNKDCFVI AEEMSNTHSF QEALRHNNFD KNGYPINKLV
310 320 330 340 350 360
KRDDHAKIIT FLIPLLVLGF AFFGFSHLHI LFALPVIILL LLASNKFIKS FLLPSYETKG
370 380 390 400 410 420
TNSASLLKSP LIAGILFGSI FWLAFVWILR ILPYTFTKRP LGNLTFCAIL CFVCYSLFLL
430 440 450 460 470 480
AFSDPGHIGS ENDHEKIRET ISNLLKEGKF DTRSFCLETW VRKPLRSKYS YLNDALILRF
490 500 510 520 530 540
DHYCPWIYND VGLKNHKLFI FFILALELGI FSFVKVCLKY FDELDMDGDC FILGDDDLCS
550 560 570 580 590 600
GLIGDRFTFL IMTWACIQAV WIFSLVIVQL FQITKGLTNS ELNALIREGR RVDIDSQTHN
610 620 630 640 650 660
EFFNTVPEGF INNKDTEEEA APPVRNNTNE RISTTFSGNL PKPRTCMGMI CAVTGLHQCV
670 680 690 700 710 720
AIIKDTFGIA RHGSSRSTNT RSLLSSISTD YGWRRNWCDF WLLSDTNTPL WKRIFFSPPS
730 740 750 760
TKALLNGKEA DYATLYEVPN KNHGSVSQLQ ELQDPLSEID DMV