Q6FIS9

PR
Gene name
PYK1 (CAGL0M12034g)
Protein name
Pyruvate kinase 1
Names
PK 1
Species
Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) (Yeast) (Torulopsis glabrata)
KEGG Pathway
cgr:CAGL0M12034g
EC number
2.7.1.40: Phosphotransferases with an alcohol group as acceptor
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-58 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q6FIS9

Entry ID Method Resolution Chain Position Source
AF-Q6FIS9-F1 Predicted AlphaFoldDB

No variants for Q6FIS9

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q6FIS9

No associated diseases with Q6FIS9

3 regional properties for Q6FIS9

Type Name Position InterPro Accession
domain Pyruvate kinase, barrel 20 - 363 IPR015793
domain Pyruvate kinase, C-terminal 381 - 498 IPR015795
active_site Pyruvate kinase, active site 236 - 248 IPR018209

Functions

Description
EC Number 2.7.1.40 Phosphotransferases with an alcohol group as acceptor
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

4 GO annotations of cellular component

Name Definition
cell surface The external part of the cell wall and/or plasma membrane.
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
extracellular region The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
fungal biofilm matrix An extracellular matrix lying external to fungal cells. The fungal biofilm matrix consists of polysaccharides, proteins, lipids, and nucleic acids. Fungal biofilms mediate adherence to host tissues, and provide protection from host immune defenses.

5 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
kinase activity Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
magnesium ion binding Binding to a magnesium (Mg) ion.
potassium ion binding Binding to a potassium ion (K+).
pyruvate kinase activity Catalysis of the reaction: = ADP + H(+) + phosphoenolpyruvate => ATP + pyruvate.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MDSRLARLTT LQTSAGEELR RTSIIGTIGP KTNNPETLVA LRKAGLNIVR MNFSHGSYEY
70 80 90 100 110 120
HKSVIDNARK SEELYPGRPL AIALDTKGPE IRTGTTTNEV DYPIPPNHEM IFTTDDKYAK
130 140 150 160 170 180
ACDDKIMYLD YKNITKVISA GRIIYVDDGV LSFEVLQVVD DKTLKVKSLN AGKICSHKGV
190 200 210 220 230 240
NLPGTDVDLP ALSEKDKADL RFGVENGVHM IFASFIRTAQ DVLTIREVLG EDGKDIKIVV
250 260 270 280 290 300
KIENQQGVNN FDEILKVTDA VMVARGDLGI EIPAPEVLAV QKKLIAKSNL AGKPVICATQ
310 320 330 340 350 360
MLESMTYNPR PTRAEVSDVG NAVLDGADCV MLSGETAKGN YPINAVTTMA ETALIAEQAI
370 380 390 400 410 420
AYLPNYDDIR NCTPKPTSTT ETVAASAVAA VFEQKAKAII VLSTSGTTAR LVSKYRPNCP
430 440 450 460 470 480
IILVTRNART ARFSHLYRGV FPFVYEKESV SDWTEDVEAR LNFGIEQAIE FGILKKGDTY
490 500
VSIQGFKAGV GHSNTLQVST A