Q6FIK3

PR
Gene name
ATM1
Protein name
Iron-sulfur clusters transporter ATM1, mitochondrial
Names
Species
Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) (Yeast) (Torulopsis glabrata)
KEGG Pathway
cgr:CAGL0M13739g
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

22-143 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q6FIK3

Entry ID Method Resolution Chain Position Source
AF-Q6FIK3-F1 Predicted AlphaFoldDB

No variants for Q6FIK3

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q6FIK3

No associated diseases with Q6FIK3

4 regional properties for Q6FIK3

Type Name Position InterPro Accession
domain ABC transporter-like, ATP-binding domain 465 - 701 IPR003439
domain AAA+ ATPase domain 490 - 678 IPR003593
domain ABC transporter type 1, transmembrane domain 140 - 429 IPR011527
conserved_site ABC transporter-like, conserved site 602 - 616 IPR017871

Functions

Description
EC Number
Subcellular Localization
  • Mitochondrion inner membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
mitochondrial inner membrane The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.

3 GO annotations of molecular function

Name Definition
ABC-type transporter activity Primary active transporter characterized by two nucleotide-binding domains and two transmembrane domains. Uses the energy generated from ATP hydrolysis to drive the transport of a substance across a membrane.
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP hydrolysis activity Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.

3 GO annotations of biological process

Name Definition
iron ion homeostasis Any process involved in the maintenance of an internal steady state of iron ions within an organism or cell.
iron-sulfur cluster assembly The incorporation of iron and exogenous sulfur into a metallo-sulfur cluster.
iron-sulfur cluster export from the mitochondrion The directed movement of iron sulfur clusters from inside the mitochondrion into the cytosol by crossing the inner mitochondrial membrane.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MLIGGAQNRL YQLRTSNILG LLRTRSALRV GSKVELRCPY NNWTNLGRSH FSSTSIPPTF
70 80 90 100 110 120
KSKTFGREKG LLAHNINVKR LSSTVSKSKL PNEDTAHNAS EKNSKKTDTK AVNISELKIL
130 140 150 160 170 180
KDLFKYIWPR GNTKVKVRVL LALALLIGAK VLNVQVPFFF KQIIDGMNVD WSDATVALPA
190 200 210 220 230 240
ALGLTIMCYG LARFGAVLFG ELRNAIFARV AQNAIRNVSL QTFEHLMKLD LGWHLSRQTG
250 260 270 280 290 300
GLTRAMDRGT KGISYVLSAM VFHIIPITFE ISVVCGILTY QFGASFAGIT FTTMLLYSIF
310 320 330 340 350 360
TIRTTAWRTR FRKEANKADN KGASVALDSL INFEAVKYFN NESYLANKYH NSLIKYRDSQ
370 380 390 400 410 420
VKVAQSLAFL NSGQSLIFTT ALTGMMYMGC TGVIGGDLTV GDLVLINQLV FQLSVPLNFL
430 440 450 460 470 480
GSVYRELKQS LIDMESLFKL RKNQVKIQNC SQPKSISKSD GPFEIKFENV TFGYDGQRKI
490 500 510 520 530 540
LKNASFTIPA GMKTAIAGPS GSGKSTVLKL VFRFYDPEEG RVLVNGVDVR EYDIDQLRKA
550 560 570 580 590 600
IGVVPQDTPL FNDTIWENVK FGRIEASDEE ITRVIDKAQL SDLIAKLPQG SSTIVGERGL
610 620 630 640 650 660
MISGGEKQRL AIARVLLKDA DIMFFDEATS ALDTHTEQSL LRTIRRNFNS GEKTSVYIAH
670 680 690 700 710 720
RLRTIADADK IIVLEEGTVR EEGTHQELLA RENSLYKELW RIQEDLDLLE DEINHEKETL
EKLNKSI