Q6FEI9

PR
Gene name
glnE
Protein name
Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme
Names
ATP:glutamine synthetase adenylyltransferase, ATase
Species
Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1)
KEGG Pathway
aci:ACIAD0596
EC number
2.7.7.42: Nucleotidyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

21-91 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q6FEI9

Entry ID Method Resolution Chain Position Source
AF-Q6FEI9-F1 Predicted AlphaFoldDB

No variants for Q6FEI9

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q6FEI9

No associated diseases with Q6FEI9

4 regional properties for Q6FEI9

Type Name Position InterPro Accession
domain Glutamate-ammonia ligase adenylyltransferase, repeated domain 31 - 276 IPR005190-1
domain Glutamate-ammonia ligase adenylyltransferase, repeated domain 553 - 805 IPR005190-2
domain PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase 297 - 436 IPR013546-1
domain PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase 825 - 916 IPR013546-2

Functions

Description
EC Number 2.7.7.42 Nucleotidyltransferases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

4 GO annotations of molecular function

Name Definition
[glutamate-ammonia-ligase] adenylyltransferase activity Catalysis of the reaction: ATP + [L-glutamate:ammonia ligase (ADP-forming)] = diphosphate + adenylyl-[L-glutamate:ammonia ligase (ADP-forming)].
[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase Catalysis of the reaction: adenylyl-[L-glutamate:ammonia ligase (ADP-forming)] + H2O = AMP + [L-glutamate:ammonia ligase (ADP-forming)].
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
magnesium ion binding Binding to a magnesium (Mg) ion.

2 GO annotations of biological process

Name Definition
metabolic process The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
regulation of glutamine family amino acid metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MQTKGCRFFM NTEQLQKTLR SSQYAEQVLG LHQLYLEQDY QIDQFAAPLS RENIFQSVEN
70 80 90 100 110 120
ELKDIQDESQ WMRVVRILRA RLMFRWIWQD ANRLTNVVSL TRELSDFADA CICAAKQFAR
130 140 150 160 170 180
APLVAKHGEP VGYDGQIQDL IVIGMGKLGA QELNLSSDID LIFAYDEQGE TNGRKSIDVQ
190 200 210 220 230 240
QFCILWGQKL IYLLDHITAD GFVFRVDMRL RPWGDGSALA ISHMALEKYL IQHGREWERY
250 260 270 280 290 300
AWIKARIISG GKHGDDLLEM TRPFVFRRYV DYSAFAAMRE MKSMIEREVA RRNIADDIKL
310 320 330 340 350 360
GAGGIREVEF IVQVFQLIYG GSKRELQDRQ CLVSLNHLGQ AGLLQSQDVI ELEDAYLFLR
370 380 390 400 410 420
RVEHAIQALN DQQTQMLPME PELRQRILDT LEYPTWDNFI EALNEKRHKV SEQFKKLIQE
430 440 450 460 470 480
EVTSPDETDT ELEQQLNAIL DETAQNLVHE FWQSNALKRL PSKAVQRLKD FWPHFIEAIL
490 500 510 520 530 540
QSEHPQMAFM RLMPLIESVM RRTVYLVMLM ESRGAMQRLV KMATVSPWIC EELTQYPVLL
550 560 570 580 590 600
DEFLSMDFEL PQRKDLEDSL RQQLLRIEID QVEDQMRVLR LFKKSNVLTV AASDVLAESP
610 620 630 640 650 660
LMKVSDALTD IAEVSVAATL NLAYQAVVKK HGYPKDASGE RCSLEHTGFA VIGYGKLGGI
670 680 690 700 710 720
ELGYGSDLDL VFIHYFDEQA ETDGSKSITG FEFAMRVAQK FLSLMTTQTL DGRVYEIDTR
730 740 750 760 770 780
LRPSGEAGLL VTSLKAFEQY QLKSAWLWEH QALVRARSIA GEAQLRQKFE SLRCQILTQS
790 800 810 820 830 840
RDENEVRDEV LKMRQKMKDH LGSSNEQKKH GIFHLKQDAG GIVDIEFMAQ YMVLAWSGAN
850 860 870 880 890 900
PDLAHFSDNV RILEDAAQAG CLSSEDATAL MHAYLRERAE SHRLALANQS MQVNAAQWRH
910 920
TREVVCKLWQ RLIDPASTMA LESE