Q6F1J8

PR
Gene name
glyQS
Protein name
Glycine--tRNA ligase
Names
Glycyl-tRNA synthetase, GlyRS
Species
Mesoplasma florum (strain ATCC 33453 / NBRC 100688 / NCTC 11704 / L1) (Acholeplasma florum)
KEGG Pathway
mfl:Mfl268
EC number
6.1.1.14: Ligases forming aminoacyl-tRNA and related compounds
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

396-451 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q6F1J8

Entry ID Method Resolution Chain Position Source
AF-Q6F1J8-F1 Predicted AlphaFoldDB

No variants for Q6F1J8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q6F1J8

No associated diseases with Q6F1J8

4 regional properties for Q6F1J8

Type Name Position InterPro Accession
domain Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) 153 - 334 IPR002314
domain Anticodon-binding 362 - 449 IPR004154
domain Aminoacyl-tRNA synthetase, class II 116 - 355 IPR006195
domain Glycyl-tRNA synthetase-like core domain 4 - 334 IPR033731

Functions

Description
EC Number 6.1.1.14 Ligases forming aminoacyl-tRNA and related compounds
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
glycine-tRNA ligase activity Catalysis of the reaction: ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly).
protein dimerization activity The formation of a protein dimer, a macromolecular structure consists of two noncovalently associated identical or nonidentical subunits.

1 GO annotations of biological process

Name Definition
glycyl-tRNA aminoacylation The process of coupling glycine to glycyl-tRNA, catalyzed by glycyl-tRNA synthetase. The glycyll-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3'-OH group of a glycine-accepting tRNA.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MEKLIAHLKS QGFIFQGSEI YGGLANSWDY GPLGVEVKNK LKQAWWNHFV RKNPYNIGLD
70 80 90 100 110 120
SSIILNSSVW KASGHIDGFN DPLIDCKKCN SRWRADKLIE EFNSEINAGV MTENQMEEFI
130 140 150 160 170 180
REQNIKCPKC QACDFTQIRK FALMFKTNQG VLEDESSSVY LRPETAQGIF INFKNAQRSL
190 200 210 220 230 240
RKKLPFGIGQ IGKSFRNEIT PGNFIFRTRE FEQMELEFFF NPSDEKDWFS YWLNEVETFL
250 260 270 280 290 300
QDKIQINKEN YRVRSHEKDE LAHYSTATSD IEFKFPFGWG ELWGVAHRGN FDLNAHQEAS
310 320 330 340 350 360
KQDLTYLDPT TNQKVLPHVI EPSVGVERMM LAILWQAYHE EDLGEGNSRI VMKLPYNLAP
370 380 390 400 410 420
YQIAVMPLQK QQNDQAQALY SNLLNNFDVT YDETGNVGKR YRRQDAIGTP FVITVDFDTP
430 440 450
ETNSVTVRER DSMEQVRINL DELEAYLKAK F