Q6F0E1

PR
Gene name
tmk
Protein name
Thymidylate kinase
Names
dTMP kinase
Species
Mesoplasma florum (strain ATCC 33453 / NBRC 100688 / NCTC 11704 / L1) (Acholeplasma florum)
KEGG Pathway
mfl:Mfl676
EC number
2.7.4.9: Phosphotransferases with a phosphate group as acceptor
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

108-189 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q6F0E1

Entry ID Method Resolution Chain Position Source
AF-Q6F0E1-F1 Predicted AlphaFoldDB

No variants for Q6F0E1

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q6F0E1

No associated diseases with Q6F0E1

8 regional properties for Q6F0E1

Type Name Position InterPro Accession
domain Cadherin, Y-type LIR-motif 722 - 780 IPR000233
domain Cadherin-like 70 - 160 IPR002126-1
domain Cadherin-like 160 - 280 IPR002126-2
domain Cadherin-like 270 - 384 IPR002126-3
domain Cadherin-like 385 - 489 IPR002126-4
domain Cadherin-like 489 - 603 IPR002126-5
conserved_site Cadherin conserved site 257 - 267 IPR020894-1
conserved_site Cadherin conserved site 477 - 487 IPR020894-2

Functions

Description
EC Number 2.7.4.9 Phosphotransferases with a phosphate group as acceptor
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
thymidylate kinase activity Catalysis of the reaction: ATP + thymidine 5'-phosphate = ADP + thymidine 5'-diphosphate.

3 GO annotations of biological process

Name Definition
dTDP biosynthetic process The chemical reactions and pathways resulting in the formation of dTDP, deoxyribosylthymine diphosphate (2'-deoxyribosylthymine5'-diphosphate).
dTTP biosynthetic process The chemical reactions and pathways resulting in the formation of dTTP, deoxyribosylthymine triphosphate.
phosphorylation The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MFITIEGMDG SGKTTALQRV KQYLEDLNYK VVMTREPGGL PLSEKIRELI LNKDGVGMEP
70 80 90 100 110 120
WTEALLFIAA RKEHLEKVIK PYLKKGYIVI SDRFMDSTTA YQGGARGLGV DYLNELQKNI
130 140 150 160 170 180
LEGFLPDLTL YFELSFEDAE KRLSARPEEK NRLDEEGRKF KEAVKLAFEE LVVKEPNRIT
190 200 210
VIDASKSPEE VFEETKKVIL EKIELWKKEK R