Q6DDW7
Gene name |
castor2 |
Protein name |
Cytosolic arginine sensor for mTORC1 subunit 2 |
Names |
GATS-like protein 2 |
Species |
Xenopus laevis (African clawed frog) |
KEGG Pathway |
xla:446578 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q6DDW7
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q6DDW7-F1 | Predicted | AlphaFoldDB |
No variants for Q6DDW7
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q6DDW7 | |||||
No associated diseases with Q6DDW7
3 regional properties for Q6DDW7
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | CASTOR, ACT domain | 72 - 140 | IPR027795-1 |
| domain | CASTOR, ACT domain | 262 - 322 | IPR027795-2 |
| domain | CASTOR1, N-terminal | 9 - 69 | IPR040778 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| negative regulation of TORC1 signaling | Any process that stops, prevents or reduces the frequency, rate or extent of TORC1 signaling. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MELHILEHRL | KVASIAKENI | QLFTYGLIKL | AFLSSKTRCK | FFSLTETPED | YTIIVDEEGF |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LELPSSEHLS | VADATWLALN | VVSGGGSSSS | SQPIGVTKIA | KSVIAPLADQ | NISVFMLSTY |
| 130 | 140 | 150 | 160 | 170 | 180 |
| QTDFILVRER | DLPFVMHTLA | AEFTILQVVN | GETVAADNLG | VTNGFVKPKL | VQRPVIHPLS |
| 190 | 200 | 210 | 220 | 230 | 240 |
| SPSNMFCVTS | LDPYTLPTVT | TLLMDVMFYS | NGVKDSVVGS | EEPDHIRFFS | FSLIEGYISL |
| 250 | 260 | 270 | 280 | 290 | 300 |
| VMDVQTQQRF | PSNLLFTSAS | GELWKMVRIG | GQPLGFDECG | IVAQISEPLA | AADIPAYYIS |
| 310 | 320 | ||||
| TFKFDHALVP | EENINGVINA | LQVSQAEKH |