Q6DCZ7

PR
Gene name
fnbp1l (toca1)
Protein name
Formin-binding protein 1-like
Names
Transducer of Cdc42-dependent actin assembly protein 1, Toca-1
Species
Xenopus laevis (African clawed frog)
KEGG Pathway
xla:446802
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

121-206 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q6DCZ7

Entry ID Method Resolution Chain Position Source
AF-Q6DCZ7-F1 Predicted AlphaFoldDB

No variants for Q6DCZ7

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q6DCZ7

No associated diseases with Q6DCZ7

6 regional properties for Q6DCZ7

Type Name Position InterPro Accession
domain FCH domain 1 - 93 IPR001060
domain SH3 domain 479 - 540 IPR001452
domain HR1 rho-binding domain 339 - 416 IPR011072
domain F-BAR domain 1 - 263 IPR031160
domain FNBP1L, SH3 domain 482 - 538 IPR035493
domain FNBP1L, F-BAR domain 5 - 256 IPR035494

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
  • Cytoplasm, cytoskeleton
  • Cytoplasm, cell cortex
  • Cytoplasmic vesicle
  • Cell membrane ; Peripheral membrane protein ; Cytoplasmic side
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

4 GO annotations of cellular component

Name Definition
cell cortex The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins.
cytoplasmic vesicle A vesicle found in the cytoplasm of a cell.
cytoskeleton A cellular structure that forms the internal framework of eukaryotic and prokaryotic cells. The cytoskeleton includes intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

1 GO annotations of molecular function

Name Definition
lipid binding Binding to a lipid.

3 GO annotations of biological process

Name Definition
autophagy The cellular catabolic process in which cells digest parts of their own cytoplasm; allows for both recycling of macromolecular constituents under conditions of cellular stress and remodeling the intracellular structure for cell differentiation.
endocytosis A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle.
signal transduction The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSWGTELWDQ FDNLEKHTQW GIDFLDKYAK FVKERLEIEQ NYAKQLRNLV KKFCPKRSAK
70 80 90 100 110 120
DEEPRFTSCL SFYNILNELN DYAGQREVVA EEIGHRVYAE IMRYSNDIKG ERKSHLHEGR
130 140 150 160 170 180
KAQQYLDMCL KQMDNSKRKF ERECREAEKA QQSYERLDND TNATKSDVEK AKQQLHLRTH
190 200 210 220 230 240
MADESKNEYA AQLQNYNAEQ HKHFYIVIPQ VYKHLQEMDE RRTIKLSECY KGFADAERKV
250 260 270 280 290 300
IPIISKCLEG MVQAAKSVDE RRDSQIVVDC FKSGFEPPGD FPFEDYSQHI YRTVSDGTIS
310 320 330 340 350 360
TPKQESLKPD PRMTVGKAKG KLWLFGKKPK GPALEDFSHL PPEQRRKRLQ QRIDELSREL
370 380 390 400 410 420
QKEMDQKDAL NKMKDVYEKN PQMGDPGSLH PKIAETTSNI ERLRMEIHKN EGWLSEVEGK
430 440 450 460 470 480
VSQRSERRHS AEANHLVAQG RESPEGSYTE DANQEGRVQP QHHAHPEFDD EFDDDEPLPA
490 500 510 520 530 540
IGHCKSLYPF DGNNEGTLAM KEGEVLYIIE EDKGDGWTRA RKQNGEEGYV PTSYIEITLE
KKQ