Q6D8T5
Gene name |
macB |
Protein name |
Macrolide export ATP-binding/permease protein MacB |
Names |
|
Species |
Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672) (Erwinia carotovora subsp. atroseptica) |
KEGG Pathway |
eca:ECA0887 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q6D8T5
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q6D8T5-F1 | Predicted | AlphaFoldDB |
No variants for Q6D8T5
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q6D8T5 | |||||
No associated diseases with Q6D8T5
6 regional properties for Q6D8T5
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | ABC transporter-like, ATP-binding domain | 6 - 244 | IPR003439 |
| domain | AAA+ ATPase domain | 34 - 221 | IPR003593 |
| domain | ABC3 transporter permease protein domain | 529 - 643 | IPR003838 |
| conserved_site | ABC transporter-like, conserved site | 146 - 160 | IPR017871 |
| domain | MacB, ATP-binding domain | 6 - 222 | IPR017911 |
| domain | MacB-like periplasmic core domain | 274 - 493 | IPR025857 |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| response to antibiotic | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antibiotic stimulus. An antibiotic is a chemical substance produced by a microorganism which has the capacity to inhibit the growth of or to kill other microorganisms. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSTSLLKLTG | ITRRFTNGEQ | DVTVLKDINL | TINQGEMVAI | VGASGSGKST | LMNILGCLDK |
| 70 | 80 | 90 | 100 | 110 | 120 |
| PSAGDYQVAG | RAVGKLDNDQ | LAELRREHFG | FIFQRYHLLG | DLTALGNVEV | PAIYAGKSRL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| ARRQRAADLL | TRLGLENRLH | YRPSQLSGGQ | QQRVSIARAL | MNAGGIILAD | EPTGALDTHS |
| 190 | 200 | 210 | 220 | 230 | 240 |
| GNEVLSILRD | LHRQGNTVVI | VTHDMTIAEH | AQRVIELRDG | EVIADRQTRP | EEATASSPEA |
| 250 | 260 | 270 | 280 | 290 | 300 |
| ASSPATSALN | QFKDRFIDAF | KMALLAMNAQ | RMRTFLTMLG | IIIGIASVVS | VVALGKGSQE |
| 310 | 320 | 330 | 340 | 350 | 360 |
| QVLANINSMG | TSTLEIFPGK | GFGDMDASAI | QTLRASDIQP | LTQQPYVHSV | TPSVSTSVTM |
| 370 | 380 | 390 | 400 | 410 | 420 |
| RYGNIAVSAS | ISGVGEQFFT | VRGYTLERGV | LFPRSSVDEL | TQDAVIDKNT | RDKLFPHGED |
| 430 | 440 | 450 | 460 | 470 | 480 |
| PIGQVILVGS | LPVRIIGVVS | KNQGGFGSDE | NLNVWVPYTT | VMKRMVGQSY | LKSITVRVKD |
| 490 | 500 | 510 | 520 | 530 | 540 |
| NVDMSIAEQR | ITDLLMQRHG | TKDFFIMNTD | SIRQMIEKTT | TTLTLLVSMI | ALISLLVGGI |
| 550 | 560 | 570 | 580 | 590 | 600 |
| GVMNIMLVSV | TERTREIGVR | MAVGARTSDI | MQQFLIEAVL | VCLFGGIAGV | ALSLAIGVLF |
| 610 | 620 | 630 | 640 | ||
| AQLSSNFAMI | YSSSSIIAAF | LCSSLIGIIF | GFFPARRAAR | MEPIHALERE |