Q6CYA2

PR
Gene name
SYF1 (KLLA0A01969g)
Protein name
Pre-mRNA-splicing factor SYF1
Names
Species
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica)
KEGG Pathway
kla:KLLA0_A01969g
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

735-798 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q6CYA2

Entry ID Method Resolution Chain Position Source
AF-Q6CYA2-F1 Predicted AlphaFoldDB

No variants for Q6CYA2

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q6CYA2

No associated diseases with Q6CYA2

9 regional properties for Q6CYA2

Type Name Position InterPro Accession
repeat HAT (Half-A-TPR) repeat 39 - 71 IPR003107-1
repeat HAT (Half-A-TPR) repeat 83 - 115 IPR003107-2
repeat HAT (Half-A-TPR) repeat 117 - 151 IPR003107-3
repeat HAT (Half-A-TPR) repeat 424 - 460 IPR003107-4
repeat HAT (Half-A-TPR) repeat 516 - 548 IPR003107-5
repeat HAT (Half-A-TPR) repeat 550 - 584 IPR003107-6
repeat HAT (Half-A-TPR) repeat 587 - 622 IPR003107-7
repeat HAT (Half-A-TPR) repeat 661 - 695 IPR003107-8
repeat HAT (Half-A-TPR) repeat 697 - 731 IPR003107-9

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
spliceosomal complex Any of a series of ribonucleoprotein complexes that contain snRNA(s) and small nuclear ribonucleoproteins (snRNPs), and are formed sequentially during the spliceosomal splicing of one or more substrate RNAs, and which also contain the RNA substrate(s) from the initial target RNAs of splicing, the splicing intermediate RNA(s), to the final RNA products. During cis-splicing, the initial target RNA is a single, contiguous RNA transcript, whether mRNA, snoRNA, etc., and the released products are a spliced RNA and an excised intron, generally as a lariat structure. During trans-splicing, there are two initial substrate RNAs, the spliced leader RNA and a pre-mRNA.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

1 GO annotations of biological process

Name Definition
mRNA splicing, via spliceosome The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MEIDKFVKEE DIPFEYGVVR ERDNAVSWSR YLATKRSAGD ELNLDWLYER CLKEIKDDWH
70 80 90 100 110 120
LWKEFLKWRI ELLNDCDIFR HKDEYNKISL LFEQCLTSCG KVGDAWIMYM EWVIQFKDLK
130 140 150 160 170 180
RIRELLGKAL RSMSWEYHEA IWRVVIDFII NELLIDNKRY ELSLEDSIYY FVHGEHSTNF
190 200 210 220 230 240
DTDLWSSSIL QRYSLICDDI EPLLIYIFKT HDWSTIVRVF EKHLSPNLKP SQTSLFELYV
250 260 270 280 290 300
SYITSMILVD NSAGVAAVVD QCIELFPFKK GELKTYLIFN LIRQGKITEA ELYLEKVISE
310 320 330 340 350 360
TKDIIEFSVL YDFWIRMEEL LTQELIQKMK DDNSEKQRLF ANIRLHADTL TSLIKNHTIR
370 380 390 400 410 420
LNDLELRREP NNIKLWLERV KLFDTISDKA KVYADAVLTV DYRLQTTPGL LGELWCQYCR
430 440 450 460 470 480
LFEEDIEKSE VLLDKATNVP FKFLVDLENV WLYWCEYRLK RSIDDAIKVL SVVLEIPDNH
490 500 510 520 530 540
ELLLQKFEKG ESPAQAAIFS SKRLWAMYLD LLEVKGNYGT AVNAYETAIL IKAATPAMFI
550 560 570 580 590 600
NYALLNESSG HQAEALAVFE RSVEIFPPSV SKSIWDIYLD VALKADITKE QKRDIFESAI
610 620 630 640 650 660
KLAASGVACV SFFEKYSDFE LNLGFHERSV EILHKGAKNI SDLESKCTLW EECINRSEKQ
670 680 690 700 710 720
LDVNHTRKLY EECIETLPNS KAIKFLLPFA ILEESRNEVA RCRALLDYGS KLLKPAQNEE
730 740 750 760 770 780
LWDFWRNFET MHGTKDSFKN MLKARRFLED TMKVNTEEVS RHADSIEFRA STAKISGSGP
790
PSAEDKGYSN TAEIDLGL