Q6CXS7

PR
Gene name
SFH5 (KLLA0A05885g)
Protein name
Phosphatidylinositol transfer protein SFH5
Names
PITP SFH5
Species
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica)
KEGG Pathway
kla:KLLA0_A05885g
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

238-297 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q6CXS7

Entry ID Method Resolution Chain Position Source
AF-Q6CXS7-F1 Predicted AlphaFoldDB

No variants for Q6CXS7

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q6CXS7

No associated diseases with Q6CXS7

2 regional properties for Q6CXS7

Type Name Position InterPro Accession
domain CRAL-TRIO lipid binding domain 93 - 258 IPR001251
domain CRAL/TRIO, N-terminal domain 30 - 74 IPR011074

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
  • Endoplasmic reticulum membrane ; Peripheral membrane protein
  • Microsome membrane ; Peripheral membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

4 GO annotations of cellular component

Name Definition
cortical endoplasmic reticulum A cortical network of highly dynamic tubules that are juxtaposed to the plasma membrane and undergo ring closure and tubule-branching movements.
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
endoplasmic reticulum membrane The lipid bilayer surrounding the endoplasmic reticulum.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

2 GO annotations of molecular function

Name Definition
metal ion binding Binding to a metal ion.
phosphatidylinositol transfer activity Removes phosphatidylinositol from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.

4 GO annotations of biological process

Name Definition
Golgi to plasma membrane protein transport The directed movement of proteins from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane.
phosphatidylinositol metabolic process The chemical reactions and pathways involving phosphatidylinositol, any glycophospholipid in which a sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol.
regulation of establishment of cell polarity Any process that modulates the frequency, rate or extent of establishment of cell polarity.
regulation of exocytosis Any process that modulates the frequency, rate or extent of exocytosis.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MPLNFETDEQ KKCYELLRAD VENIVKETGY DELYGHKLTP DDQFYEEVIV DNLIYKFCRA
70 80 90 100 110 120
NQFEIEGAKS QLKKTLKWRK EFKPLHAAFS ETHDSLLNDV CAITVSEEND PNQKVVSWNL
130 140 150 160 170 180
YGLLVKHKEV FEDTDKFLRF RIGLMERGLQ LLDFASEDNY LMTQVHDYNN VSMWRLDPAI
190 200 210 220 230 240
KKCSKAIIEV FQDFYPETLF SKFFVNVPYV MTWLYEIVKR FVSEDTRKKF IVMSDGTQMK
250 260 270 280 290
DYLKVLPKEY GGEATLNSSK LENIEPNAYV SYLLTQCGGE EPAETTAPEQ EKETATA