Q6CX96

PR
Gene name
ATM1
Protein name
Iron-sulfur clusters transporter ATM1, mitochondrial
Names
Species
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica)
KEGG Pathway
kla:KLLA0_A10131g
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

24-135 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q6CX96

Entry ID Method Resolution Chain Position Source
AF-Q6CX96-F1 Predicted AlphaFoldDB

No variants for Q6CX96

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q6CX96

No associated diseases with Q6CX96

4 regional properties for Q6CX96

Type Name Position InterPro Accession
domain ABC transporter-like, ATP-binding domain 456 - 692 IPR003439
domain AAA+ ATPase domain 481 - 669 IPR003593
domain ABC transporter type 1, transmembrane domain 130 - 421 IPR011527
conserved_site ABC transporter-like, conserved site 593 - 607 IPR017871

Functions

Description
EC Number
Subcellular Localization
  • Mitochondrion inner membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
mitochondrial inner membrane The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.

3 GO annotations of molecular function

Name Definition
ABC-type transporter activity Primary active transporter characterized by two nucleotide-binding domains and two transmembrane domains. Uses the energy generated from ATP hydrolysis to drive the transport of a substance across a membrane.
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP hydrolysis activity Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.

3 GO annotations of biological process

Name Definition
iron ion homeostasis Any process involved in the maintenance of an internal steady state of iron ions within an organism or cell.
iron-sulfur cluster assembly The incorporation of iron and exogenous sulfur into a metallo-sulfur cluster.
iron-sulfur cluster export from the mitochondrion The directed movement of iron sulfur clusters from inside the mitochondrion into the cytosol by crossing the inner mitochondrial membrane.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MIMFRSLSVT PVWKAGLSLS HRSIPINSRL SSVRNYISIG CANKTGSRLL RSAGVSSQYK
70 80 90 100 110 120
DFRRFNSSSN GNGTDKNASV APKTEVKKIV PPKPSTNGKS KTPTISELRI MKDLFKYIWP
130 140 150 160 170 180
SGDNKVKIRV LIALALLIGA KLLNVQVPFF FKQTIDSMNI EWGPDVATVL PVAITMTILS
190 200 210 220 230 240
YGAARFGAVM FGELRNAVFA KVAQNAIRKV SLQTFQHLMK LDLGWHLSRQ TGGLTRAMDR
250 260 270 280 290 300
GTKGISYVLS AMVFHMIPIT FEISVVCGIL TYQFGSSFAA MTFVTMLLYS FFTFKTTAWR
310 320 330 340 350 360
TEFRRSANRA DNKAASVALD SLINFEAVKY FNNEEYLANK YHQSLSKYRD SQIKVAQSLA
370 380 390 400 410 420
FLNAGQNFIF TSALTAMMYM GASGVMEGAL TVGDLVLINQ LVFQLSVPLN FLGSVYRELK
430 440 450 460 470 480
QSLIDMESLF KLQKNPILIK NTERPLMLPE HLPCEIKFEN VTFGYQPDRN ILKNATFTIA
490 500 510 520 530 540
PGKKTAIVGP SGSGKSTILR LVFRFYDPQQ GRILLDGKDI RELDLDELRR IVGVVPQDTP
550 560 570 580 590 600
LFNDTIWENV KFGRINATDN EIVTAIEKAQ LSDLIHKLPK GTETIVGERG LMISGGEKQR
610 620 630 640 650 660
LAIARVLLKD TPIMFFDEAT SALDTHTEQS LLKTIKENFS DVAKTSVYIA HRLRTIADAD
670 680 690 700 710
KIIVLENGAV REEGTHNALL ANPNSLYSEL WNIQENLDML EDELEDELKL EKEPRTSKKD