Q6CWX3

PR
Gene name
SNX41 (KLLA0B00803g)
Protein name
Sorting nexin-41
Names
Species
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica)
KEGG Pathway
kla:KLLA0_B00803g
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-126 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q6CWX3

Entry ID Method Resolution Chain Position Source
AF-Q6CWX3-F1 Predicted AlphaFoldDB

No variants for Q6CWX3

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q6CWX3

No associated diseases with Q6CWX3

2 regional properties for Q6CWX3

Type Name Position InterPro Accession
domain Phox homology 101 - 221 IPR001683
domain Snx41 /Atg20, PX domain 108 - 218 IPR044106

Functions

Description
EC Number
Subcellular Localization
  • Endosome membrane ; Peripheral membrane protein
  • Endomembrane system ; Peripheral membrane protein
  • Endosome and other perivacuolar punctate structures
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasmic side of endosome membrane The side (leaflet) of the endosome membrane that faces the cytoplasm.
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

1 GO annotations of molecular function

Name Definition
phosphatidylinositol-3-phosphate binding Binding to phosphatidylinositol-3-phosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3' position.

3 GO annotations of biological process

Name Definition
intracellular protein transport The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell.
retrograde transport, endosome to Golgi The directed movement of membrane-bounded vesicles from endosomes back to the trans-Golgi network where they are recycled for further rounds of transport.
selective autophagy The macroautophagy process in which specific structures are targeted by the autophagy process.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MNVFDGSDEE DNNPFSGTTH LYASGIAAVT DGPDDYDFTE PSINGSSDEN AQSNAVAEPI
70 80 90 100 110 120
EETDEPAEEI DDDTLQTWRF ASAELSRSSA FETSYTNLLG QGKNPEVIRI VDAGQYRDIY
130 140 150 160 170 180
GKYAIGYKIE FGGIVVTRRY SEFDSLRQSL CRLLPTIIIP PIPSKHPIIK YLFNPLHAKK
190 200 210 220 230 240
DIKIIERRQR LLSRFLNNCH KVREIRNHIV FQKFLNPEYF WKEVLNTPPI SILPMNNLLA
250 260 270 280 290 300
PPLNPTKPSP IHLLLPTPTV LTMRKHEQLI GRNDVMEIKF ADYDSDLIRY KAILQPLNKT
310 320 330 340 350 360
VRSIRSNIQT YSAVLSELGA YFNAFSLENS VFQVSALFEQ MNRLSMGIEK TGQAIDVNYV
370 380 390 400 410 420
SAEIFSEAIM ISLEEGSKEM LQFIHEAQRV LHFRNFKQEQ FYTIETTIKK RKDRIRELKE
430 440 450 460 470 480
ADLQAVRLGE ALKLNAEESP TVAQVMDSMT RKSANKNHTD KQIMGLFRSS ASPNNKSGSD
490 500 510 520 530 540
SISSEVEPHL LTKDERVVQV NKLEKELEKL NECFKLIEKD LQQVNESMDN SLNNLEKYFH
550 560 570
EKWFLIFREL AHNITSWLKD CSESWKNAKQ SIDSI