Q6CWE8
Gene name |
FPR3 (KLLA0B04664g) |
Protein name |
FK506-binding protein 3 |
Names |
Peptidyl-prolyl cis-trans isomerase, PPIase, Rotamase |
Species |
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica) |
KEGG Pathway |
kla:KLLA0_B04664g |
EC number |
5.2.1.8: Cis-trans isomerases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q6CWE8
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q6CWE8-F1 | Predicted | AlphaFoldDB |
No variants for Q6CWE8
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q6CWE8 | |||||
No associated diseases with Q6CWE8
5 regional properties for Q6CWE8
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | Actinin-type actin-binding domain, conserved site | 211 - 235 | IPR001589 |
| domain | Calponin homology domain | 122 - 239 | IPR001715-1 |
| domain | Calponin homology domain | 267 - 370 | IPR001715-2 |
| domain | Calponin homology domain | 392 - 498 | IPR001715-3 |
| domain | Calponin homology domain | 513 - 621 | IPR001715-4 |
Functions
| Description | ||
|---|---|---|
| EC Number | 5.2.1.8 | Cis-trans isomerases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleolus | A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| peptidyl-prolyl cis-trans isomerase activity | Catalysis of the reaction: peptidyl-proline (omega=180) = peptidyl-proline (omega=0). |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSDLLPLAAY | NLNIEPYTPT | PAIDVTTPVT | VRITMAAIDP | EALDDEKNPS | TLRIIKRNPD |
| 70 | 80 | 90 | 100 | 110 | 120 |
| YDDEDDAGGL | LGDYDEDELD | ISEEEEEEEE | KSKSKKGKGK | GKSKKQEEEE | EEEEEDEDEG |
| 130 | 140 | 150 | 160 | 170 | 180 |
| DEELIEIDTD | DEFQEFVLAT | LSPKTQYQQS | LDIVIAPEEE | VQFIVTGSYR | VSLTGNYVKH |
| 190 | 200 | 210 | 220 | 230 | 240 |
| PFDAPGYDDE | DDDEEDDESY | DEDEDDYLTP | DEEADLEELE | DASDVEAKIQ | ELVEKEQSKS |
| 250 | 260 | 270 | 280 | 290 | 300 |
| KKNNKRKQPE | PEEEEEEEEE | EEEEQKLVEE | TKKNKKAKKE | KKVEFKKDLE | EGPTKKEEKK |
| 310 | 320 | 330 | 340 | 350 | 360 |
| EEKKEKPKTK | VLEGGIIIED | RVTGKGKACK | KGSKVGMRYI | GKLKNGKVFD | KNTSGKPFVF |
| 370 | 380 | 390 | 400 | 410 | |
| NLGRGEVIKG | WDIGVAGMAV | GGERRIVIPA | PYAYGKQALP | GIPANSELTF | DVKLVSLK |