Q6CVU2
Gene name |
ALG1 (KLLA0B09405g) |
Protein name |
Chitobiosyldiphosphodolichol beta-mannosyltransferase |
Names |
Asparagine-linked glycosylation protein 1, Beta-1,4-mannosyltransferase, GDP-Man:GlcNAc2-PP-dolichol mannosyltransferase, GDP-mannose-dolichol diphosphochitobiose mannosyltransferase |
Species |
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica) |
KEGG Pathway |
kla:KLLA0_B09405g |
EC number |
2.4.1.142: Hexosyltransferases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q6CVU2
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q6CVU2-F1 | Predicted | AlphaFoldDB |
No variants for Q6CVU2
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q6CVU2 | |||||
No associated diseases with Q6CVU2
1 regional properties for Q6CVU2
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Glycosyl transferase, family 1 | 259 - 421 | IPR001296 |
Functions
| Description | ||
|---|---|---|
| EC Number | 2.4.1.142 | Hexosyltransferases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| endoplasmic reticulum membrane | The lipid bilayer surrounding the endoplasmic reticulum. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| chitobiosyldiphosphodolichol beta-mannosyltransferase activity | Catalysis of the reaction: GDP-mannose + chitobiosyldiphosphodolichol = GDP + beta-D-mannosylchitobiosyldiphosphodolichol. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| oligosaccharide-lipid intermediate biosynthetic process | The chemical reactions and pathways resulting in the formation of an oligosaccharide-lipid intermediate, such as a molecule of dolichol-P-man or dolicol-P-Glc used in N-linked glycosylation. |
| protein N-linked glycosylation | A protein glycosylation process in which a carbohydrate or carbohydrate derivative unit is added to a protein via the N4 atom of peptidyl-asparagine, the omega-N of arginine, or the N1' atom peptidyl-tryptophan. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSVFGFDNIP | TWLWWLLAIY | LATPFVLYVV | QPYLFYEGKS | TKTRILIVVL | GDLGHSPRIL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| YHARSFSKAG | FQVELSGYVD | SDIPTDILDD | DNIEIHGLKK | YGSEKGLLVK | ALKQGLQLCS |
| 130 | 140 | 150 | 160 | 170 | 180 |
| MFWKLRAVDY | ILLQNPPTIP | ILPIAVVVKT | FSRAKLIIDW | HNLGYTILQM | KFKDQFLHPL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| VLLAYLIEWI | FAKFANYHLT | VTKAMKTYLV | EKFGIDGKKI | AVLYDRPGKQ | FSPLKEADDR |
| 250 | 260 | 270 | 280 | 290 | 300 |
| EALLKQEFIA | KYIPKEFDIS | KDKIFVTSTS | FTPDEDISVL | IGSFKIYENS | FQKFDQTLPR |
| 310 | 320 | 330 | 340 | 350 | 360 |
| ILCFITGKGP | LQEKIVKQVQ | DFKWDRVQVE | FLWLSSEDYP | KLLRLCDYGV | SLHTSSSGLD |
| 370 | 380 | 390 | 400 | 410 | 420 |
| LPMKILDMFG | SGLPVICMNY | PVLDELVQQN | VNGLKFADRR | ELHEALIFSV | KDEQVHQEIK |
| 430 | 440 | ||||
| RGALRESKNR | WNESWESALS | ELKIIHK |