Q6CUZ6
Gene name |
MGR1 (KLLA0C01089g) |
Protein name |
Mitochondrial inner membrane i-AAA protease complex subunit MGR1 |
Names |
|
Species |
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica) |
KEGG Pathway |
kla:KLLA0_C01089g |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q6CUZ6
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q6CUZ6-F1 | Predicted | AlphaFoldDB |
No variants for Q6CUZ6
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q6CUZ6 | |||||
No associated diseases with Q6CUZ6
No regional properties for Q6CUZ6
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q6CUZ6 | |||
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| i-AAA complex | Protease complex of the mitochondrial inner membrane whose catalytic residues lie on the intermembrane space side of the inner membrane; involved in mitochondrial protein turnover. Contains a subunit belonging to the AAA family of ATP-dependent metalloproteases. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| misfolded protein binding | Binding to a misfolded protein. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| protein quality control for misfolded or incompletely synthesized proteins | The chemical reactions and pathways resulting in the breakdown of misfolded or attenuated proteins. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAIYTSGTQS | DNSEPVGNDP | KFYTRPSLGL | KLWGPLVPSS | DNTTGLWSLV | AIQTGLGLFL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| MQRFRKLGKK | WVKRDIADFP | SLNRFSTTHG | DMYMTRHIPV | QFGGTHSFNI | RVGTRTGFWY |
| 130 | 140 | 150 | 160 | 170 | 180 |
| SERFRTIRRV | TYLLAGTLIL | SQSMLEVSRL | TLLKYDPWVE | EAKSVREKQF | FNDIVKYYHE |
| 190 | 200 | 210 | 220 | 230 | 240 |
| GVDSTKFKAK | DELSGQSISL | NLPEVKQSIA | VARAQAQAEN | LVTKWFGPLD | YKPQSFSEFL |
| 250 | 260 | 270 | 280 | 290 | 300 |
| DKLEYYLNMT | DFLNNLRRQK | KNDKINSQLV | KLEEENKRNR | QRIHTLMAHA | PARAIRTNQE |
| 310 | 320 | 330 | 340 | 350 | 360 |
| VQDIYAIRKV | LLHHDTESPN | DIPLTEIWAI | YNPWTNLALD | TALSIKFFPS | VIFNEDYYEH |
| 370 | 380 | ||||
| QKRLKDSEHV | TSIENSEDER | KP |