Q6CUI6
Gene name |
DBP9 (KLLA0C04576g) |
Protein name |
ATP-dependent RNA helicase DBP9 |
Names |
|
Species |
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica) |
KEGG Pathway |
kla:KLLA0_C04576g |
EC number |
3.6.4.13: Acting on ATP; involved in cellular and subcellular movement |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q6CUI6
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q6CUI6-F1 | Predicted | AlphaFoldDB |
No variants for Q6CUI6
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q6CUI6 | |||||
No associated diseases with Q6CUI6
4 regional properties for Q6CUI6
Functions
| Description | ||
|---|---|---|
| EC Number | 3.6.4.13 | Acting on ATP; involved in cellular and subcellular movement |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleolus | A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome. |
6 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| ATP hydrolysis activity | Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient. |
| DNA helicase activity | Unwinding of a DNA helix, driven by ATP hydrolysis. |
| DNA/RNA helicase activity | Unwinding of a DNA/RNA duplex, i.e. a double helix in which a strand of DNA pairs with a complementary strand of RNA, driven by ATP hydrolysis. |
| RNA binding | Binding to an RNA molecule or a portion thereof. |
| RNA helicase activity | Unwinding of an RNA helix, driven by ATP hydrolysis. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule from the pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, 5.8S rRNA, and Large Subunit (LSU) in that order from 5' to 3' along the primary transcript. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAQTSASQGY | IDDSSSFDSF | HLDSRLSQAI | RSIGFKHPTL | IQSSAIPLAL | QEKRDIIAKA |
| 70 | 80 | 90 | 100 | 110 | 120 |
| STGSGKTLAY | LIPVIQTILD | HKKADQNDEG | ATLGVILVPT | RELAQQVLEV | VEKLIVFCSQ |
| 130 | 140 | 150 | 160 | 170 | 180 |
| EIKCLNLSSG | NVSGNLLKSL | LTENPEILIA | TPAKLVDLLD | AQDVNIDRLK | FLVIDEVDLV |
| 190 | 200 | 210 | 220 | 230 | 240 |
| LTFGYQEDLT | KISERLPLRK | SLQTFLMSAT | LNDDIQHLKQ | QFCRSPAILK | LNDDEVNKDQ |
| 250 | 260 | 270 | 280 | 290 | 300 |
| TKLIQYYVKV | GEFDKFLLCY | VIFKLGLIKG | KTLIFVNNID | RGYRLKLVLE | QFGIKSCILN |
| 310 | 320 | 330 | 340 | 350 | 360 |
| SELPANSRQH | IVEEFNKNVY | QLLIATDDTE | YIKEEDEDLE | SEKTEDGLVE | VVDDSTVTTK |
| 370 | 380 | 390 | 400 | 410 | 420 |
| DNAKKQKKPK | LNVEKDKEYG | VSRGVDFKNV | ACVLNFDLPT | TAKSYVHRIG | RTARAGKSGI |
| 430 | 440 | 450 | 460 | 470 | 480 |
| SISFVVPLKE | FGKHKPSMIK | SAKKDEKILG | RIIKQQAKLG | FELQPYNFDI | KQVEGFRYRM |
| 490 | 500 | 510 | 520 | 530 | 540 |
| EDGFRAVTQV | AIREARIKEL | KQELLASEKL | KRHFEENPHD | LESLRHDKEL | HPARVQQHLK |
| 550 | 560 | 570 | 580 | 590 | |
| RVPDYLLPET | ARKDNKKIGF | VPFHKNSHRK | NGRVVKKKGN | VQRKGKSDPL | KSFK |