Q6CT00
Gene name |
KLLA0C16533g |
Protein name |
DNA damage-binding protein CMR1 |
Names |
|
Species |
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica) |
KEGG Pathway |
kla:KLLA0_C16533g |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q6CT00
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q6CT00-F1 | Predicted | AlphaFoldDB |
No variants for Q6CT00
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q6CT00 | |||||
No associated diseases with Q6CT00
4 regional properties for Q6CT00
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| repeat | WD40 repeat | 184 - 221 | IPR001680-1 |
| repeat | WD40 repeat | 326 - 366 | IPR001680-2 |
| repeat | WD40 repeat | 382 - 420 | IPR001680-3 |
| conserved_site | WD40 repeat, conserved site | 351 - 365 | IPR019775 |
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| chromatin | The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome. |
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| nuclear periphery | The portion of the nuclear lumen proximal to the inner nuclear membrane. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| DNA binding | Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| cellular response to DNA damage stimulus | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism. |
| regulation of DNA damage checkpoint | Any process that modulates the frequency, rate or extent of a DNA damage checkpoint. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MGELTEFQKK | RLENIKRNND | LLKKLNLNNV | SSQIKREAGV | EDEHLDRKRK | KKAGSAKKAV |
| 70 | 80 | 90 | 100 | 110 | 120 |
| KKEPKPAAIP | TRRSRRLRGE | NVDGNGIPNV | NDNQLLKMGQ | SDSTPELEAI | DELKNTALSG |
| 130 | 140 | 150 | 160 | 170 | 180 |
| DVKLSDLIKS | ENEEELLDKF | KSFANKNFSS | GDFFKELQQQ | QVPTPEIKQL | QEDFDLKLYD |
| 190 | 200 | 210 | 220 | 230 | 240 |
| IFQPNEIKLT | AERISATFFH | PSVDKKLVIC | GDTAGNVGLW | NVRETQPEDE | LEEPDITKVK |
| 250 | 260 | 270 | 280 | 290 | 300 |
| LFTKNVGRID | TYATDSSRLL | AASYDGYLRS | INLQDMNSEE | ILVLKNEYDD | PLGISDFQFN |
| 310 | 320 | 330 | 340 | 350 | 360 |
| YNDPNVLFMT | TLSGEFTTFD | VRTKPTEINL | KRLSDKKIGS | FSINPKRPYE | IATGSLDRTL |
| 370 | 380 | 390 | 400 | 410 | 420 |
| KIWDTRKIVN | KPEWSQYEDF | ASHEIVATYD | SRLSVSAVSY | SPMDETLVCN | GYDDTIRLFD |
| 430 | 440 | 450 | 460 | 470 | 480 |
| VSGTLPEDLQ | PKLTLKHNCQ | TGRWTSILKA | RFKLNMDVFA | IANMKRAIDI | YTSSGVQLAH |
| 490 | 500 | 510 | |||
| LPTATVPAVI | SWHPTQNWVV | GGNSSGKAFL | FT |