Q6CRQ9
Gene name |
ISU1 (KLLA0D07161g) |
Protein name |
Iron sulfur cluster assembly protein 1, mitochondrial |
Names |
Iron sulfur cluster scaffold protein 1 |
Species |
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica) |
KEGG Pathway |
kla:KLLA0_D07161g |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q6CRQ9
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q6CRQ9-F1 | Predicted | AlphaFoldDB |
No variants for Q6CRQ9
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q6CRQ9 | |||||
No associated diseases with Q6CRQ9
1 regional properties for Q6CRQ9
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | NIF system FeS cluster assembly, NifU, N-terminal | 13 - 165 | IPR002871 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| mitochondrial matrix | The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation. |
4 GO annotations of molecular function
| Name | Definition |
|---|---|
| 2 iron, 2 sulfur cluster binding | Binding to a 2 iron, 2 sulfur (2Fe-2S) cluster; this cluster consists of two iron atoms, with two inorganic sulfur atoms found between the irons and acting as bridging ligands. |
| ATPase activator activity | Binds to and increases the activity of an ATP hydrolysis activity. |
| ferrous iron binding | Binding to a ferrous iron ion, Fe(II). |
| zinc ion binding | Binding to a zinc ion (Zn). |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| cellular iron ion homeostasis | Any process involved in the maintenance of an internal steady state of iron ions at the level of a cell. |
| iron-sulfur cluster assembly | The incorporation of iron and exogenous sulfur into a metallo-sulfur cluster. |
| tRNA wobble uridine modification | The process in which a uridine in position 34 of a tRNA is post-transcriptionally modified. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MFRGQMFAVQ | RMGSALMHGG | GGGTRIIGVA | AARATAPTVG | SSPSMASARF | YHPKVIDHYT |
| 70 | 80 | 90 | 100 | 110 | 120 |
| NPRNVGSLDK | NLPNVGTGLV | GAPACGDVMK | LQIQVNDETG | VIENVKFKTF | GCGSAIASSS |
| 130 | 140 | 150 | 160 | 170 | |
| YMTELVRGKT | LEDAAKIKNT | EIARELSLPP | VKLHCSMLAE | DAIKAAIKDY | QAKRPTTQLK |