Q6CRH6
Gene name |
CCZ1 (KLLA0D08998g) |
Protein name |
Vacuolar fusion protein CCZ1 |
Names |
|
Species |
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica) |
KEGG Pathway |
kla:KLLA0_D08998g |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q6CRH6
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q6CRH6-F1 | Predicted | AlphaFoldDB |
No variants for Q6CRH6
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q6CRH6 | |||||
No associated diseases with Q6CRH6
1 regional properties for Q6CRH6
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | CCZ1/INTU/HSP4, first Longin domain | 4 - 113 | IPR043987 |
Functions
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| Mon1-Ccz1 complex | A protein complex that functions as a guanine nucleotide exchange factor (GEF) and converts Rab-GDP to Rab-GTP. In S. cerevisiae, this complex consists of at least Mon1 and Ccz1, and serves as a GEF for the Rab Ypt7p. |
| multivesicular body membrane | The lipid bilayer surrounding a multivesicular body. |
| vacuolar membrane | The lipid bilayer surrounding the vacuole and separating its contents from the cytoplasm of the cell. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| autophagy | The cellular catabolic process in which cells digest parts of their own cytoplasm; allows for both recycling of macromolecular constituents under conditions of cellular stress and remodeling the intracellular structure for cell differentiation. |
| protein transport | The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
| vesicle-mediated transport | A cellular transport process in which transported substances are moved in membrane-bounded vesicles; transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The process begins with a step that directs a substance to the forming vesicle, and includes vesicle budding and coating. Vesicles are then targeted to, and fuse with, an acceptor membrane. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSVQFIVLFR | DDDDNKDDSC | KLLLYHDLTA | HMLSTNEKEQ | KIGIIKGMWR | FSNEFSQSND |
| 70 | 80 | 90 | 100 | 110 | 120 |
| YCHVELDSYS | MLVLEVEPSY | YLALGFENTH | NSQWPKYKVR | LSQCYQFFAM | QHGKMQDIED |
| 130 | 140 | 150 | 160 | 170 | 180 |
| KTLSGLLNEH | FIPFWDEINL | IPDYFLMQDI | NTAIDDKMFP | CCQFADALNS | ISEVKDWQNY |
| 190 | 200 | 210 | 220 | 230 | 240 |
| LKNNVLLSEE | NYLNIKDVCV | YHLPKNNKNT | KEYGFITNFD | PQFKSLPTLS | NWLVGIDSMY |
| 250 | 260 | 270 | 280 | 290 | 300 |
| GTVSSHGLAG | TMSLTETEQQ | IELDAEEAHH | EQPPNIKTVW | DNVTLPITFT | MDALKDIGQL |
| 310 | 320 | 330 | 340 | 350 | 360 |
| TGVSNSLSLF | TNMKPSWNLW | SSSSENGAGS | AKLDDKDEYS | WLISPLNPSF | LPKVYQMRKF |
| 370 | 380 | 390 | 400 | 410 | 420 |
| YLQFDDWSQY | NILFWKFKDV | IVAVIVDPSF | KKISEESFLM | KLQEELWNGI | SLFYENTGFE |
| 430 | 440 | 450 | 460 | 470 | 480 |
| KRQCSFDYTI | LFKEEGKYYS | SIPRWKNGLD | ESDTALKLVI | KGLDETLQFL | TNNANRKSSV |
| 490 | 500 | 510 | 520 | 530 | 540 |
| ATVTEVGHDM | SLTDHPIPSD | PSKGEDGTEK | TDKSESSIFS | KLNESQLVEL | NKELMVILGT |
| 550 | 560 | 570 | 580 | 590 | 600 |
| RSLTVWYKDA | NTKERMLKLN | NGLMVYLLEN | NRKLVLIIKN | WFIDSQQKTK | SKRSTDMIES |
| 610 | |||||
| LGKDVSTWWN | RIKDHEPL |