Q6CPQ9
Gene name |
EFT1 (KLLA0E02926g) |
Protein name |
Elongation factor 2 |
Names |
EF-2 |
Species |
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica) |
KEGG Pathway |
kla:KLLA0_E02993g |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q6CPQ9
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q6CPQ9-F1 | Predicted | AlphaFoldDB |
No variants for Q6CPQ9
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q6CPQ9 | |||||
No associated diseases with Q6CPQ9
7 regional properties for Q6CPQ9
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Elongation factor EFG, domain V-like | 723 - 818 | IPR000640 |
| domain | Translational (tr)-type GTP-binding domain | 17 - 344 | IPR000795 |
| domain | Translation elongation factor EFTu-like, domain 2 | 395 - 470 | IPR004161 |
| domain | Small GTP-binding protein domain | 20 - 164 | IPR005225 |
| domain | Translation elongation factor EFG/EF2, domain IV | 604 - 721 | IPR005517 |
| conserved_site | Tr-type G domain, conserved site | 58 - 73 | IPR031157 |
| domain | Elongation Factor G, domain II | 487 - 548 | IPR041095 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| GTP binding | Binding to GTP, guanosine triphosphate. |
| GTPase activity | Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate. |
| translation elongation factor activity | Functions in chain elongation during polypeptide synthesis at the ribosome. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MVAFTVDQIR | SLMDKVTNVR | NMSVIAHVDH | GKSTLTDSLV | QRAGIISAAK | AGEARFTDTR |
| 70 | 80 | 90 | 100 | 110 | 120 |
| KDEQERGITI | KSTAISLFSE | MSDDDVKDIK | QKTDGNAFLI | NLIDSPGHVD | FSSEVTAALR |
| 130 | 140 | 150 | 160 | 170 | 180 |
| VTDGALVVVD | TVEGVCVQTE | TVLRQSLAER | IKPVVVINKV | DRALLELQVS | KEDLYQSFSR |
| 190 | 200 | 210 | 220 | 230 | 240 |
| TVESVNVIIS | TYADEVLGDV | QVYPQRGTVA | FGSGLHGWAF | TVRQFANRYS | KKFGVDREKM |
| 250 | 260 | 270 | 280 | 290 | 300 |
| MDRLWGDSYF | NPKTKKWTNK | ERDADGKPLE | RAFNMFVLDP | IFRLFAAIMN | FKKEEIPVLL |
| 310 | 320 | 330 | 340 | 350 | 360 |
| EKLEINLKGD | EKELEGKNLL | KVVMRKFLPA | ADALLEMIIL | HLPSPVTAQN | YRAEQLYEGP |
| 370 | 380 | 390 | 400 | 410 | 420 |
| SDDPACIAIK | NCDPKSDLML | YVSKMVPTSD | KGRFYAFGRV | FAGTVKSGQK | VRIQGPNFIP |
| 430 | 440 | 450 | 460 | 470 | 480 |
| GKKEDLFIKA | IQRAVLMMGR | FVEPIDDCPA | GNIIGLVGID | QFLLKTGTLT | TFEGAHNMKV |
| 490 | 500 | 510 | 520 | 530 | 540 |
| MKFSVSPVVQ | VAVEVKNAND | LPKLVEGLKR | LSKSDPCVLV | SMSESGEHIV | AGTGELHLEI |
| 550 | 560 | 570 | 580 | 590 | 600 |
| CLQDLENDHA | GIPLKISPPV | VAYRETVEGE | SSQTALSKSP | NKHNRIYLKA | QPIDEEVSLA |
| 610 | 620 | 630 | 640 | 650 | 660 |
| IEGGKINPRD | DFKARARIMA | DEFGWDVTDA | RKIWCFGPDG | NGPNLVVDQT | KAVQYLNEIK |
| 670 | 680 | 690 | 700 | 710 | 720 |
| DSVVAAFQWA | TKEGPIFGEQ | MRSVRVNILD | VTLHADAIHR | GGGQIIPTMR | RATYAGFLLA |
| 730 | 740 | 750 | 760 | 770 | 780 |
| EPKIQEPVFL | VEIQCPEQAI | GGIYSVLNKK | RGQVVSEEQR | PGTPLFTVKA | YLPINESFGF |
| 790 | 800 | 810 | 820 | 830 | 840 |
| TGELRQATGG | QAFPQMVFDH | WATLGTDPLD | PSTKAGEIVL | AARKRQGMKE | EVPGWQEYYD |
| KL |