Q6CNW3

PR
Gene name
RLP24 (KLLA0E09416g)
Protein name
Ribosome biogenesis protein RLP24
Names
Species
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica)
KEGG Pathway
kla:KLLA0_E09439g
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

126-198 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q6CNW3

Entry ID Method Resolution Chain Position Source
AF-Q6CNW3-F1 Predicted AlphaFoldDB

No variants for Q6CNW3

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q6CNW3

No associated diseases with Q6CNW3

1 regional properties for Q6CNW3

Type Name Position InterPro Accession
domain TRASH domain 6 - 44 IPR011017

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
  • Nucleus
  • Shuttles between the nucleus and the cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
nucleolus A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
preribosome, large subunit precursor A preribosomal complex consisting of 27SA, 27SB, and/or 7S pre-rRNA, 5S rRNA, ribosomal proteins including late-associating large subunit proteins, and associated proteins; a precursor of the eukaryotic cytoplasmic large ribosomal subunit.

2 GO annotations of molecular function

Name Definition
ATPase activator activity Binds to and increases the activity of an ATP hydrolysis activity.
ATPase binding Binding to an ATPase, any enzyme that catalyzes the hydrolysis of ATP.

3 GO annotations of biological process

Name Definition
assembly of large subunit precursor of preribosome The aggregation, arrangement and bonding together of a set of components to form the large subunit precursor of the preribosome.
positive regulation of ATP-dependent activity Any process that activates or increases the rate of an ATP-dependent activity.
ribosomal large subunit biogenesis A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a large ribosomal subunit; includes transport to the sites of protein synthesis.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MRVYACHFCS SPCYPGHGIM FVRNDAKEFR FCRSKCHKAF KQRRNPRKLR WTKAFRKAAG
70 80 90 100 110 120
KELAVDSTLT FAQRRNVPVR YNRELVATTL KAMSRIEEIR QRRERAFYKN RMKGNNERDF
130 140 150 160 170 180
LRDKALVESN PELLRLREVE LARQAAKEEA IEQASDEEMD IESEAESEVE SESEAEEQLQ
190
KQKILLKNKR KNSKRIAF