Q6CN76
Gene name |
GPI10 (KLLA0E14762g) |
Protein name |
GPI mannosyltransferase 3 |
Names |
GPI mannosyltransferase III, GPI-MT-III, Glycosylphosphatidylinositol-anchor biosynthesis protein 10 |
Species |
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica) |
KEGG Pathway |
kla:KLLA0_E14719g |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q6CN76
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q6CN76-F1 | Predicted | AlphaFoldDB |
No variants for Q6CN76
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q6CN76 | |||||
No associated diseases with Q6CN76
No regional properties for Q6CN76
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q6CN76 | |||
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| endoplasmic reticulum membrane | The lipid bilayer surrounding the endoplasmic reticulum. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| alpha-1,2-mannosyltransferase activity | Catalysis of the transfer of a mannose residue to an oligosaccharide, forming an alpha-(1->2) linkage. |
| glycolipid mannosyltransferase activity | Catalysis of the transfer of an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-D-mannosyl-D-mannose linkage. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| GPI anchor biosynthetic process | The chemical reactions and pathways resulting in the formation of a glycosylphosphatidylinositol (GPI) anchor that attaches some membrane proteins to the lipid bilayer of the cell membrane. The phosphatidylinositol group is linked via the C-6 hydroxyl residue of inositol to a carbohydrate chain which is itself linked to the protein via an ethanolamine phosphate group, its amino group forming an amide linkage with the C-terminal carboxyl of the protein. Some GPI anchors have variants on this canonical linkage. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSNQVPLKRL | FKVILVIRCV | QALLTRTFFQ | ADEFWQSLEP | AHYMAFGYGE | LTWEWSFGLR |
| 70 | 80 | 90 | 100 | 110 | 120 |
| SYAFPLIFQI | GYTLVKYAAI | SCELIVQTAT | DWVLLFVANV | IPNSEFGWEM | VQEMRSFPEE |
| 130 | 140 | 150 | 160 | 170 | 180 |
| IRGFIEYQGV | IYAPKLIMAV | LAAIGEFHVI | LLAEKLYKLT | MDKSDDSKGS | DKKHSTVINF |
| 190 | 200 | 210 | 220 | 230 | 240 |
| TLVATVSNFF | NCFFITRSFI | NSFEMILTSV | SLYYWDWTSG | EHIESFDFLK | SLIIGTFTVL |
| 250 | 260 | 270 | 280 | 290 | 300 |
| QRPTNAFIWL | ILGGYMILNL | VLSKRWRKLF | SLLIKVICAS | FISISTNLCI | DYYFYGYITI |
| 310 | 320 | 330 | 340 | 350 | 360 |
| PVLKFIKFNC | TSSLSKFYGV | APWNFHVFQS | LPIVAGYSLP | LLIHSFFCSL | TKKRFLSPLV |
| 370 | 380 | 390 | 400 | 410 | 420 |
| NPFLQIKTVV | LLNVILYSLI | PHKEFRFIYP | LQPFFIILSV | FDGIWLLQKY | GSTATTRTME |
| 430 | 440 | 450 | 460 | 470 | 480 |
| FFSQVMWILP | VVSMVASMLL | STLHESGTVA | VMDYLHSIRN | IDSIGFIMPC | HSTPWQSHFH |
| 490 | 500 | 510 | 520 | 530 | 540 |
| RNDVKELWAI | TCSPPLHLLT | DPDANAKLPF | YMDESDYLYD | NISKFMYQHF | PPVFRKSLRS |
| 550 | 560 | 570 | 580 | 590 | 600 |
| PGKQYTYEWP | EYLVIFEDLD | SQFMNDYLVD | SMYIEETRFF | NSLVHWDKRR | SGDIIIYHKM |
| P |