Q6CMK9

PR
Gene name
KXD1 (KLLA0E19427g)
Protein name
Biogenesis of lysosome-related organelles complex 1 subunit KXD1
Names
BLOC-1 subunit KXD1, KxDL homolog
Species
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica)
KEGG Pathway
kla:KLLA0_E19427g
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-178 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q6CMK9

Entry ID Method Resolution Chain Position Source
AF-Q6CMK9-F1 Predicted AlphaFoldDB

No variants for Q6CMK9

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q6CMK9

No associated diseases with Q6CMK9

1 regional properties for Q6CMK9

Type Name Position InterPro Accession
domain KxDL domain 80 - 164 IPR019371

Functions

Description
EC Number
Subcellular Localization
  • Endosome
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
BLOC-1 complex A protein complex required for the biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes and platelet dense granules. Many of the protein subunits are conserved between mouse and human; the mouse complex contains the Pallidin, Muted, Cappuccino, Dysbindin, Snapin, BLOS1, BLOS2, AND BLOS3 proteins.
endosome A vacuole to which materials ingested by endocytosis are delivered.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

2 GO annotations of biological process

Name Definition
endosome organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of endosomes.
regulation of protein localization Any process that modulates the frequency, rate or extent of any process in which a protein is transported to, or maintained in, a specific location.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MDEHRSRTPS IDSRNYAIPE ADYLPAGIDI DRNGVSESDD SSDDDAQSSL FPTESSGTLW
70 80 90 100 110 120
MNQIQDTPMF DSSKFLFESV NNAINDIDFS ESLAIQAKTS ALINSKSREL KGLIKQLQEK
130 140 150 160 170
VDYYNERFKR GAVVSSQLKV NLQMLSKRIA TLDDLFSKQF PIEYNQSKEK VMERTLND