Q6CLZ9

PR
Gene name
SEC62 (KLLA0E24200g)
Protein name
Translocation protein SEC62
Names
Species
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica)
KEGG Pathway
kla:KLLA0_E24157g
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

23-133 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q6CLZ9

Entry ID Method Resolution Chain Position Source
AF-Q6CLZ9-F1 Predicted AlphaFoldDB

No variants for Q6CLZ9

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q6CLZ9

No associated diseases with Q6CLZ9

2 regional properties for Q6CLZ9

Type Name Position InterPro Accession
active_site RNA methyltransferase TrmA, active site 371 - 402 IPR030390
conserved_site RNA methyltransferase TrmA, conserved site 424 - 434 IPR030391

Functions

Description
EC Number
Subcellular Localization
  • Endoplasmic reticulum membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
integral component of endoplasmic reticulum membrane The component of the endoplasmic reticulum membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
Sec62/Sec63 complex A protein complex involved in the posttranslational targeting of proteins to the ER. In yeast, it is a tetrameric complex consisting of Sec62p, Sec63p, Sec71p and Sec72p.
translocon complex A protein complex that constitutes a specific site of protein translocation across the endoplasmic reticulum, which involves the signal recognition particle receptor. The complex contains a core heterotrimer of alpha, beta and gamma subunits, and may contain additional proteins.

1 GO annotations of molecular function

Name Definition
protein transmembrane transporter activity Enables the transfer of a protein from one side of a membrane to the other.

1 GO annotations of biological process

Name Definition
post-translational protein targeting to membrane, translocation The process in which a protein translocates through the ER membrane posttranslationally.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSEPSPQSTI AIANLLRTHS DLKQRQGLFQ SRLVDFFRYK RFVRALKSDK YKAKSKKQPE
70 80 90 100 110 120
LYPAVTSDED ARNIFVSLIK AQFVVPAVKL HSAECKEHGL KPNKSYPNLL LSNKATLQPD
130 140 150 160 170 180
EYYVWSYNPK SIYDYLTVIG IIVGVLAFVC YPLWPPYMKR GTYYLSIAAL ALIGVFFGIA
190 200 210 220 230 240
IVRLIVYLLS LAAVSEKGGF WLFPNLFEDC GVIESFKPLY GFGEKECYSF LKKEKRKHRS
VAKKQK