Q6CKV6
Gene name |
NOP12 (KLLA0F07799g) |
Protein name |
Nucleolar protein 12 |
Names |
|
Species |
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica) |
KEGG Pathway |
kla:KLLA0_F07799g |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q6CKV6
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q6CKV6-F1 | Predicted | AlphaFoldDB |
No variants for Q6CKV6
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q6CKV6 | |||||
No associated diseases with Q6CKV6
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleolus | A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome. |
| preribosome | Any complex of pre-rRNAs, ribosomal proteins, and associated proteins formed during ribosome biogenesis. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| rRNA binding | Binding to a ribosomal RNA. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule from the pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, 5.8S rRNA, and Large Subunit (LSU) in that order from 5' to 3' along the primary transcript. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSALNNLFGN | SKSDAAGTSS | IAALFSKPNH | VDERKVKSKA | RTVLTEPEQD | KDEQEEENVQ |
| 70 | 80 | 90 | 100 | 110 | 120 |
| ESASTVSEGV | EKEQEEQEEQ | PKKKKKKTKK | NDEENDNLEV | QYYSKVLGDS | KSKDEPKDEP |
| 130 | 140 | 150 | 160 | 170 | 180 |
| KDDSSDSDNE | DEATAVDKSS | ITGTESESAK | VINLKEKELA | KAERTIFIGN | VPNEVITSKK |
| 190 | 200 | 210 | 220 | 230 | 240 |
| VYKEFKKLLS | KDPRSENDDH | DDGEEDEEEE | ESKTKDVKFN | VESIRFRSIA | FEEALPRKVA |
| 250 | 260 | 270 | 280 | 290 | 300 |
| FVHQKLHKSR | DSINAYAVYG | SSNPVKIMCQ | YLNGKVFNDH | HLRVDSVTHP | SPHDKRRSVF |
| 310 | 320 | 330 | 340 | 350 | 360 |
| VGNLDFEEVE | ESLWKHFEPC | GDIEYVRIIR | DSKTNMGKGF | AYVQFKDFQS | VSKALLLHEK |
| 370 | 380 | 390 | 400 | 410 | 420 |
| KIHEGKKARK | LRISRCKNMR | KAQGNQSSLQ | NNKLNDQQRT | KLGRAKKVLG | KADRAKLGEE |
| 430 | 440 | 450 | 460 | ||
| LTIEGLRASK | GETTPVLKRT | KNRSKTGRVT | KRSIAFKKQN | AQ |