Q6CKU5

PR
Gene name
MDM10
Protein name
Mitochondrial distribution and morphology protein 10
Names
Mitochondrial inheritance component MDM10
Species
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica)
KEGG Pathway
kla:KLLA0_F08041g
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

76-153 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q6CKU5

Entry ID Method Resolution Chain Position Source
AF-Q6CKU5-F1 Predicted AlphaFoldDB

No variants for Q6CKU5

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q6CKU5

No associated diseases with Q6CKU5

No regional properties for Q6CKU5

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q6CKU5

Functions

Description
EC Number
Subcellular Localization
  • Mitochondrion outer membrane ; Multi-pass membrane protein
  • The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria-endoplasmic reticulum junctions
  • These foci are often found next to mtDNA nucleoids
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
ERMES complex A protein complex that links the endoplasmic reticulum with mitochondria and may have a role in promoting exchange of calcium and phospholipids between the two organelles.
integral component of mitochondrial outer membrane The component of the mitochondrial outer membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
SAM complex A large complex of the mitochondrial outer membrane that mediates sorting of some imported proteins to the outer membrane and their assembly in the membrane; functions after import of incoming proteins by the mitochondrial outer membrane translocase complex.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

6 GO annotations of biological process

Name Definition
establishment of mitochondrion localization The directed movement of the mitochondrion to a specific location.
mitochondrial genome maintenance The maintenance of the structure and integrity of the mitochondrial genome; includes replication and segregation of the mitochondrial chromosome.
mitochondrial outer membrane translocase complex assembly The aggregation, arrangement and bonding together of a set of components to form a mitochondrial outer membrane translocase complex.
mitochondrion-endoplasmic reticulum membrane tethering The attachment of a mitochondrion and an endoplasmic reticulum via molecular tethers that physically bridge their respective membranes and attach them to each other. The tethering may facilitate exchange of metabolites between the organelles.
phospholipid transport The directed movement of phospholipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Phospholipids are any lipids containing phosphoric acid as a mono- or diester.
protein insertion into mitochondrial outer membrane The process comprising the insertion of proteins from outside the organelle into the mitochondrial outer membrane, mediated by large outer membrane translocase complexes.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MLEYMDYVLR QFEECTSWNK DNSYENIVGT SRNILQFDIP TALKVQVSNR ATPYSYNTLE
70 80 90 100 110 120
LTNNKTINGS LTYLYTNCEN LDQFIEGSSS VHLQQMTQSF RYIEPYYHHY KNNSKLEVPK
130 140 150 160 170 180
VPELPISLAY GRMFYPSSSL EAMYIRRFPN YYQFILKCSS SKSGSSILTM YLQKNTGINC
190 200 210 220 230 240
QELIFSTNEA LLGYRFVHNF VSAGSKSNLS LYNNSSLSIG SEIWCALLNL SPGCSTTLRY
250 260 270 280 290 300
CSHATNTGKP LIFTLSLNPL YGHVSSTYSI KTHENLTFCT KYDFNIYSIQ SNLTLGMELW
310 320 330 340 350 360
KNSSSIPVER PSEPVETIED WPQLSHDKTP MYYHLLTRTE NSGASSQRLL KDLNLTFQSS
370 380 390 400 410 420
LQKINKERNV IENFNERYSE ANFTQVFKVS TSLRDMNLRL LWEGKIRGFL ISAGAELTQP
430 440 450
PEISTNGLDS LEHQNWSLIS PSKFGIQLQY SA