Q6CIU0
Gene name |
NCS2 |
Protein name |
Cytoplasmic tRNA 2-thiolation protein 2 |
Names |
|
Species |
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica) |
KEGG Pathway |
kla:KLLA0_F24002g |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q6CIU0
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q6CIU0-F1 | Predicted | AlphaFoldDB |
No variants for Q6CIU0
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q6CIU0 | |||||
No associated diseases with Q6CIU0
No regional properties for Q6CIU0
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q6CIU0 | |||
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| nucleotidyltransferase activity | Catalysis of the transfer of a nucleotidyl group to a reactant. |
| tRNA binding | Binding to a transfer RNA. |
6 GO annotations of biological process
| Name | Definition |
|---|---|
| invasive growth in response to glucose limitation | A growth pattern exhibited by budding haploid cells under certain growth conditions, in which cells retain the typical axial budding pattern of haploids, but become elongated and fail to separate after division; during growth on a solid substrate, this results in penetration of cells into the agar medium. An example of this process is found in Saccharomyces cerevisiae. |
| protein urmylation | Covalent attachment of the ubiquitin-like protein URM1 to another protein. |
| pseudohyphal growth | The process in which cells grow as a chain of physically attached, elongated cells in response to an environmental stimulus or stimuli. |
| tRNA thio-modification | The addition a sulfur atom to a nucleotide in a tRNA molecule. |
| tRNA wobble position uridine thiolation | The process in which a uridine residue at position 34 in the anticodon of a tRNA is post-transcriptionally thiolated at the C2 position. This process involves transfer of a sulfur from cysteine to position C2 by several steps. |
| tRNA wobble uridine modification | The process in which a uridine in position 34 of a tRNA is post-transcriptionally modified. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MVICKRCKLL | DATLVSRKEP | FCDECFVKFI | SLKQRKQMMS | DDYFQDIFKI | SYPDKKRGQA |
| 70 | 80 | 90 | 100 | 110 | 120 |
| EADKQNQDSN | VLVPLSLGSS | SLAVLDILND | TLLEQKQTHR | GKTGFHVEVI | TICGQAEFEE |
| 130 | 140 | 150 | 160 | 170 | 180 |
| VRGKIELLKS | KYKENSDKIL | FHIVDRNQFF | AVPFDLQEIT | LYIDNFNTLV | RSSNNPSTTV |
| 190 | 200 | 210 | 220 | 230 | 240 |
| EKVLASAPNK | TAKEDLLNII | YTHLIKKFAL | QRNFKAILWG | HSMTKLADEV | ISLTVKGRGA |
| 250 | 260 | 270 | 280 | 290 | 300 |
| EIAGYLDDSS | LDSKYNTAFR | NFHPGRDVLL | SEIDAYCHIK | GLSQFSHNYV | VQDTLFYDKF |
| 310 | 320 | 330 | 340 | 350 | 360 |
| VDKPTKNVKL | IKNMTMNELA | RQYFDNIEGD | YSNVISTVVR | TGAKLSNPDN | ELNQIMHCSI |
| 370 | 380 | 390 | 400 | 410 | 420 |
| CNAIIYKNPV | NWLDGITVSK | PFVIHNEEEL | TNYNAWEAAN | PDKAEKLNKM | SDTPAKNVGV |
| 430 | 440 | 450 | 460 | ||
| CYGCITTLTG | MKDRKLEWIR | RDDKAELTAV | LQEYEIPSDD | SEQ |