Q6CIH3
Gene name |
ERB1 |
Protein name |
Ribosome biogenesis protein ERB1 |
Names |
Eukaryotic ribosome biogenesis protein 1 |
Species |
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica) |
KEGG Pathway |
kla:KLLA0_F26653g |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q6CIH3
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q6CIH3-F1 | Predicted | AlphaFoldDB |
No variants for Q6CIH3
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q6CIH3 | |||||
No associated diseases with Q6CIH3
6 regional properties for Q6CIH3
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | SH3 domain | 478 - 537 | IPR001452 |
| domain | PTB/PI domain | 31 - 164 | IPR006020 |
| domain | Tensin/EPS8 phosphotyrosine-binding domain | 35 - 164 | IPR013625 |
| domain | Epidermal growth factor receptor kinase substrate, phosphotyrosine-binding domain | 32 - 162 | IPR033928 |
| domain | Eps8, SH3 domain | 482 - 535 | IPR035462 |
| domain | SAM domain | 626 - 687 | IPR041418 |
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleoplasm | That part of the nuclear content other than the chromosomes or the nucleolus. |
| PeBoW complex | A protein complex that is involved in coordinating ribosome biogenesis with cell cycle progression. In human, it is composed of Pes1, Bop1, and WDR12; in Saccharomyces the proteins are known as Nop7p, Erb1 and Ytm1 respectively. |
| preribosome, large subunit precursor | A preribosomal complex consisting of 27SA, 27SB, and/or 7S pre-rRNA, 5S rRNA, ribosomal proteins including late-associating large subunit proteins, and associated proteins; a precursor of the eukaryotic cytoplasmic large ribosomal subunit. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| large ribosomal subunit rRNA binding | Binding to large ribosomal subunit RNA (LSU rRNA), a constituent of the large ribosomal subunit. In S. cerevisiae, this is the 25S rRNA. |
| ribonucleoprotein complex binding | Binding to a complex of RNA and protein. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | Any process involved in the maturation of an rRNA molecule originally produced as part of a tricistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript. |
| maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule from the pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, 5.8S rRNA, and Large Subunit (LSU) in that order from 5' to 3' along the primary transcript. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MARKNSSLNG | SESAELVVKK | RVLEESELSD | SEDERIEVDG | LIDEEASENE | AEEAEDDDSD |
| 70 | 80 | 90 | 100 | 110 | 120 |
| AEFNRLLAEE | ENGQEEEYNT | SDFSEEGDAF | SITDKLSNVK | LTVIPETSDE | GIVRTKYSDG |
| 130 | 140 | 150 | 160 | 170 | 180 |
| RPRILKSEIN | PVYDSDDSDA | EAKNTIGNIP | LSAYDEMPHI | GYDINGKRIM | RPAKGSALDQ |
| 190 | 200 | 210 | 220 | 230 | 240 |
| LLESIELPEG | WTGLLDKDSG | ASLNLTEEEL | ELINKLQNNQ | QTDESVNPYE | PLIDWFTRHE |
| 250 | 260 | 270 | 280 | 290 | 300 |
| SVMPVTAVPE | PKRRFVPSKH | EAKRVMKIVK | AIREGRIIPP | KKLKELREKE | EQDSHNYDLW |
| 310 | 320 | 330 | 340 | 350 | 360 |
| GDAEEISEHV | MNLRAPKLPP | PTNEESYNPP | EEYLLTPEEI | DAWEKMEPSE | RERNFVPHKF |
| 370 | 380 | 390 | 400 | 410 | 420 |
| AALRKVPGYS | ESVRERFERS | LDLYLAPRVR | KNKLNIDPES | LIPELPSTKD | LRPFPIRCST |
| 430 | 440 | 450 | 460 | 470 | 480 |
| VYVGHKGKIR | TMSIDPTGLW | LATGSDDGTV | RVWEILTGRE | VYQVTILNAE | ENNDDHIDVV |
| 490 | 500 | 510 | 520 | 530 | 540 |
| EWNPDSTTGI | LAVTAGENIF | LLVPPIFGFE | IENTGKSKIE | YGFGFDTFGN | VKKSNLNVNS |
| 550 | 560 | 570 | 580 | 590 | 600 |
| DDEDDGAESH | AVKKQVAQWN | KPTERQAAND | ICIVITCRKS | VKKLSWHRKG | DYFVTVQPDS |
| 610 | 620 | 630 | 640 | 650 | 660 |
| GNTSVLIHQL | SKHLTQSPFK | KSKGIIMDAK | FHPFKPQLLV | CSQRYVRIYD | LSQQVLIKKL |
| 670 | 680 | 690 | 700 | 710 | 720 |
| LPGARWLSTI | DIHPRGDNLI | ASSFDKRVLW | HDLDLASTPY | KTLRYHEKAV | RSVSFHKKLP |
| 730 | 740 | 750 | 760 | 770 | 780 |
| LFCSAADDGN | IHVFHATVYD | DLMKNPMIVP | LKKLTGHKIV | NSLGVLDTIW | HPREAWLFSA |
| 790 | |||||
| GADKTARLWT | T |