Q6CIB4
Gene name |
GBU1 |
Protein name |
Guanidinobutyrase |
Names |
|
Species |
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica) |
KEGG Pathway |
kla:KLLA0_F27995g |
EC number |
3.5.3.7: In linear amidines |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q6CIB4
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q6CIB4-F1 | Predicted | AlphaFoldDB |
No variants for Q6CIB4
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q6CIB4 | |||||
No associated diseases with Q6CIB4
1 regional properties for Q6CIB4
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| binding_site | Ureohydrolase, manganese-binding site | 288 - 309 | IPR020855 |
Functions
| Description | ||
|---|---|---|
| EC Number | 3.5.3.7 | In linear amidines |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| guanidinobutyrase activity | Catalysis of the reaction: 4-guanidinobutanoate + H(2)O = 4-aminobutanoate + urea. |
| metal ion binding | Binding to a metal ion. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| arginine catabolic process | The chemical reactions and pathways resulting in the breakdown of arginine, 2-amino-5-(carbamimidamido)pentanoic acid. |
| regulation of nitrogen compound metabolic process | Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds. |
| regulation of primary metabolic process | Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism involving those compounds formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MKVAGFILGA | LIQFSLTEGH | VEQNENANLT | EMWGEDWPFS | GIQTFAHLPH | HKCLIDMEKK |
| 70 | 80 | 90 | 100 | 110 | 120 |
| FDIGVIGVPF | DTAVSFRGGA | RFGPQAIRKA | SQRQTSMRGF | NFRADINPYQ | DWASVVDCGD |
| 130 | 140 | 150 | 160 | 170 | 180 |
| VPVTPMDNCL | ALKMMTAAYE | NLLSHESQTS | DNNLPPRFVT | LGGDHSIILP | ALRALRKTYG |
| 190 | 200 | 210 | 220 | 230 | 240 |
| RLAVIHFDSH | LDTWAPSKYP | SFWHSDTSEF | THGSMLWIAH | NEGLLTENNN | IHAGLRTRLS |
| 250 | 260 | 270 | 280 | 290 | 300 |
| GSSFEDYDDD | DKVGFHRIEA | DEIMDGGIKS | IVEKIKSKIP | SDVPVYISVD | IDVLDPSAAP |
| 310 | 320 | 330 | 340 | 350 | 360 |
| GTGTMEVGGW | MTRELIRIIR | ELEDLNLVGA | DIVEVSPPFD | PTEITSLAGA | QIAYELITNM |
| 370 | 380 | 390 | 400 | ||
| VKKGPIDPEL | IKHNLELSDK | LTQGQQLLGF | SSPTDELNDK | IQKEQFVLQA |