Q6CH90

PR
Gene name
SUB2 (YALI0A11157g)
Protein name
ATP-dependent RNA helicase SUB2
Names
Species
Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica)
KEGG Pathway
yli:YALI0A11157g
EC number
3.6.4.13: Acting on ATP; involved in cellular and subcellular movement
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-86 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q6CH90

Entry ID Method Resolution Chain Position Source
AF-Q6CH90-F1 Predicted AlphaFoldDB

No variants for Q6CH90

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q6CH90

No associated diseases with Q6CH90

4 regional properties for Q6CH90

Type Name Position InterPro Accession
domain Helicase, C-terminal 275 - 436 IPR001650
domain DEAD/DEAH box helicase domain 82 - 249 IPR011545
domain Helicase superfamily 1/2, ATP-binding domain 76 - 279 IPR014001
domain RNA helicase, DEAD-box type, Q motif 57 - 85 IPR014014

Functions

Description
EC Number 3.6.4.13 Acting on ATP; involved in cellular and subcellular movement
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
spliceosomal complex Any of a series of ribonucleoprotein complexes that contain snRNA(s) and small nuclear ribonucleoproteins (snRNPs), and are formed sequentially during the spliceosomal splicing of one or more substrate RNAs, and which also contain the RNA substrate(s) from the initial target RNAs of splicing, the splicing intermediate RNA(s), to the final RNA products. During cis-splicing, the initial target RNA is a single, contiguous RNA transcript, whether mRNA, snoRNA, etc., and the released products are a spliced RNA and an excised intron, generally as a lariat structure. During trans-splicing, there are two initial substrate RNAs, the spliced leader RNA and a pre-mRNA.

4 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP hydrolysis activity Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.
RNA binding Binding to an RNA molecule or a portion thereof.
RNA helicase activity Unwinding of an RNA helix, driven by ATP hydrolysis.

2 GO annotations of biological process

Name Definition
mRNA export from nucleus The directed movement of mRNA from the nucleus to the cytoplasm.
mRNA splicing, via spliceosome The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSHEGEEELL DYSDSEEIAL PSTTVESGSN GDAKAETTTV KEENTEQKGS YVGIHSTGFR
70 80 90 100 110 120
DFLLKPELLR AIVDCGFEHP SEVQQVCIPQ SILGTDVLCQ AKAGVGKTAV FVLSTLQQLE
130 140 150 160 170 180
PVPGECSVVV LCHTRELAYQ IMNEYARFSK YLPDVKTAVF YGGSPIQKDI ELIQNKETSP
190 200 210 220 230 240
HVIVATPGRL HALVRDKHLR LGNVKTFVID ECDKVLDQID MRRDVQEIFR VTPRQKQVMM
250 260 270 280 290 300
FSATLSQEIR PICKKFMSSP LEILVDDEGK LTLHGLQQYY VDVEEKSKNR KLGDLLDNLE
310 320 330 340 350 360
FNQVIIFVKS TSRANGLSQV LNANGFPCTA VHSGIPQEER IARYKEFKEF KKRICVSTDV
370 380 390 400 410 420
FGRGIDIERI NLAINYDLPA EADQYLHRVG RAGRFGTKGL AISFVSTPED KEVLAKIQER
430 440
FEVNIAPYPA EGVDPSTYMN S