Q6CH58

PR
Gene name
RRP3
Protein name
ATP-dependent rRNA helicase RRP3
Names
Species
Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica)
KEGG Pathway
yli:YALI0A12133g
EC number
3.6.4.13: Acting on ATP; involved in cellular and subcellular movement
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-60 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q6CH58

Entry ID Method Resolution Chain Position Source
AF-Q6CH58-F1 Predicted AlphaFoldDB

No variants for Q6CH58

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q6CH58

No associated diseases with Q6CH58

6 regional properties for Q6CH58

Type Name Position InterPro Accession
conserved_site ATP-dependent RNA helicase DEAD-box, conserved site 212 - 220 IPR000629
domain Helicase, C-terminal 277 - 437 IPR001650
domain DEAD/DEAH box helicase domain 88 - 255 IPR011545
domain Helicase superfamily 1/2, ATP-binding domain 83 - 281 IPR014001
domain RNA helicase, DEAD-box type, Q motif 64 - 92 IPR014014
domain DDX47/Rrp3, DEAD-box helicase domain 65 - 267 IPR044765

Functions

Description
EC Number 3.6.4.13 Acting on ATP; involved in cellular and subcellular movement
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

4 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP hydrolysis activity Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.
RNA binding Binding to an RNA molecule or a portion thereof.
RNA helicase activity Unwinding of an RNA helix, driven by ATP hydrolysis.

1 GO annotations of biological process

Name Definition
rRNA processing Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAKATEKRVK RAKKEESGSE SEDNDAIAQE ILDTTKSDNE EEEPKKSSKN YTSVEVDESE
70 80 90 100 110 120
EQTKTFKDLG VIDSICETCE ELKFTKPTPI QAQSIPYALE GRDIIGLAQT GSGKTAAFAI
130 140 150 160 170 180
PVLQSLYENP QPLYCVVLAP TRELAYQISE TFEALGSAMG LRTAVVVGGM NMMTQAVALS
190 200 210 220 230 240
KKPHVIVATP GRLVDHLENT KGFSLRTLKF LVMDEADRLL DMEFGPSLDK ILKVIPRQRN
250 260 270 280 290 300
TYLFSATMTS KVEKLQRASL VDPVRVAVST KYQTADNLLQ YMVFCPFKHK DTHLVYLVSE
310 320 330 340 350 360
NAGNSMIIFA RTKSDTQRIS LLLRNLGYGA IPLHGDLSQT ARLGALNKFK SGSRNILIAT
370 380 390 400 410 420
DVASRGLDIP AVDLVINYDI PSDSKSYIHR VGRTARAGRA GKSVALVSQY DLELYLRIEG
430 440 450 460 470
ALGKKLDSYP LESEAVMLFS ERVAEASRAA IQEMKGEDGT KKRSKFDKKR RRDEMDIGEQ