Q6CEW9

PR
Gene name
MRD1 (YALI0B12276g)
Protein name
Multiple RNA-binding domain-containing protein 1
Names
Species
Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica)
KEGG Pathway
yli:YALI0B12276g
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

66-319 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q6CEW9

Entry ID Method Resolution Chain Position Source
AF-Q6CEW9-F1 Predicted AlphaFoldDB

No variants for Q6CEW9

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q6CEW9

No associated diseases with Q6CEW9

5 regional properties for Q6CEW9

Type Name Position InterPro Accession
domain RNA recognition motif domain 2 - 89 IPR000504-1
domain RNA recognition motif domain 301 - 379 IPR000504-2
domain RNA recognition motif domain 485 - 557 IPR000504-3
domain RNA recognition motif domain 605 - 688 IPR000504-4
domain RNA recognition motif domain 703 - 780 IPR000504-5

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
nuclear speck A discrete extra-nucleolar subnuclear domain, 20-50 in number, in which splicing factors are seen to be localized by immunofluorescence microscopy.
nucleolus A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
ribonucleoprotein complex A macromolecular complex that contains both RNA and protein molecules.

1 GO annotations of molecular function

Name Definition
RNA binding Binding to an RNA molecule or a portion thereof.

2 GO annotations of biological process

Name Definition
mRNA splicing, via spliceosome The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced.
rRNA processing Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSRLIVKNLP PYLDEAGLKK HFSTVKDPKS AGFAPSDITD VKVVRARDGK TRRFGFVGFR
70 80 90 100 110 120
SDETAEAAVK YFDTSFINST KISVAVAMTF TDPNVPLSSR ERKRQAAQRA REDAEDDREA
130 140 150 160 170 180
KKARYLEKPM TIDDINGLGN ASDPRLADYL DAMQVRSNAK TWANNDAGAV ANEPQVIQST
190 200 210 220 230 240
ASDDEYDEFT GKGDDEIDED EDEEEESENK KDDDNEEAEE DEEDPVIEDG LAADPGVSDM
250 260 270 280 290 300
DWLRQRQTRI KEGEPEEDRE NRHTESKSEG KKGKGNAPKA ATPVDEEPSE DPTIVSIRKT
310 320 330 340 350 360
GRLFLRNLLY TAKEEDFRQL FSQYGELEEV HLPINTKTGQ CKGFAHVQFE DPENAIAAYE
370 380 390 400 410 420
AQDGKIFQGR LLHILPGKPK KDYNRLDEHD LKNLPLKKQQ ELKRKAEAAK QQFSWNSLYM
430 440 450 460 470 480
NQDAVMESVA KSMGIKKSEL IDPDSSDAAV KQALAEATVI GDVKSYFEKM GVDLASFDNK
490 500 510 520 530 540
DRDDRVILVK NFPFGTTQPE IAEMFSEYGD LYKVMMPPAG TIAIVIFKHI PDARAAFAKL
550 560 570 580 590 600
AFRRFKTSIL YLEKGPKNLL PNEKMESDEV EHVKQDKIVT IEDKLSASDV MDTGSNDERP
610 620 630 640 650 660
ATASTSVFVK NLNFKTTSRV LTDAFKALDG FLVAQVKMKP DSKNKGKFLS MGFGFVEFSS
670 680 690 700 710 720
KEAAEIAQKA MDGHVLDGHK LQLKISNRGQ DEETTETKKA IDSKILIKNL PFEATKKDVQ
730 740 750 760 770 780
KLFGAFGSLK TVRVPKKFNS ESRGFAFAEY VSAKEAEHAM SALQGTHLLG RRLVLQYAQA
790 800 810 820
DASNAEEEIE RMQATVSKQA AQRSFADMKL AGEGKRRVDL EGEDEEEF