Q6CEU0

PR
Gene name
PAM18 (TIM14, YALI0B12958g)
Protein name
Mitochondrial import inner membrane translocase subunit TIM14
Names
Presequence translocated-associated motor subunit PAM18
Species
Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica)
KEGG Pathway
yli:YALI0B12958g
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-115 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q6CEU0

Entry ID Method Resolution Chain Position Source
AF-Q6CEU0-F1 Predicted AlphaFoldDB

No variants for Q6CEU0

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q6CEU0

No associated diseases with Q6CEU0

1 regional properties for Q6CEU0

Type Name Position InterPro Accession
domain DnaJ domain 95 - 141 IPR001623

Functions

Description
EC Number
Subcellular Localization
  • Mitochondrion inner membrane ; Single-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
PAM complex, Tim23 associated import motor Protein complex located on the matrix side of the mitochondrial inner membrane and associated with the TIM23 mitochondrial import inner membrane translocase complex (GO:0005744); ATPase motor activity to drive import of proteins into the mitochondrial matrix.

1 GO annotations of molecular function

Name Definition
ATPase activator activity Binds to and increases the activity of an ATP hydrolysis activity.

1 GO annotations of biological process

Name Definition
protein import into mitochondrial matrix The import of proteins across the outer and inner mitochondrial membranes into the matrix. Unfolded proteins enter the mitochondrial matrix with a chaperone protein; the information required to target the precursor protein from the cytosol to the mitochondrial matrix is contained within its N-terminal matrix-targeting sequence. Translocation of precursors to the matrix occurs at the rare sites where the outer and inner membranes are close together.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSTTPVQPLQ SEPLMDSETG VAPQIEAPQV PEGPKKGIDE QIFDYFAEHP VQATAATLVG
70 80 90 100 110 120
LYALGAVFKR PAAGARGQFF KGGFENKMGP SEALQILSLR DAGLTMNKLK GQHRKIMLLN
130 140
HPDRGGSPYV ATKINEAKSV LEKRGGLK