Q6CCY2

PR
Gene name
ARX1 (YALI0C05599g)
Protein name
Probable metalloprotease ARX1
Names
Associated with ribosomal export complex protein 1
Species
Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica)
KEGG Pathway
yli:YALI0C05599g
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

368-439 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q6CCY2

Entry ID Method Resolution Chain Position Source
AF-Q6CCY2-F1 Predicted AlphaFoldDB

No variants for Q6CCY2

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q6CCY2

No associated diseases with Q6CCY2

1 regional properties for Q6CCY2

Type Name Position InterPro Accession
domain Signal transduction response regulator, receiver domain 33 - 161 IPR001789

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

4 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
nucleolus A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
nucleoplasm That part of the nuclear content other than the chromosomes or the nucleolus.
preribosome, large subunit precursor A preribosomal complex consisting of 27SA, 27SB, and/or 7S pre-rRNA, 5S rRNA, ribosomal proteins including late-associating large subunit proteins, and associated proteins; a precursor of the eukaryotic cytoplasmic large ribosomal subunit.

2 GO annotations of molecular function

Name Definition
metal ion binding Binding to a metal ion.
metallopeptidase activity Catalysis of the hydrolysis of peptide bonds by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.

2 GO annotations of biological process

Name Definition
proteolysis The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.
ribosomal large subunit export from nucleus The directed movement of a ribosomal large subunit from the nucleus into the cytoplasm.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSLARSTALL DEKNTLTSSV TDKYRLAGKI TQTCLQHIIQ TVLTQYETYT VGEMCRMGDE
70 80 90 100 110 120
FLERATTAVY KSVAEKGIAQ PVRIEKQEFV GGVSPENGDK FQGGMLAPGD LVKISLGVYI
130 140 150 160 170 180
DGYTAQVTQT EVVRHVPNTS AGETEQPLTG SPADAVCASY LASEAVIAYL AQVTDPNPGK
190 200 210 220 230 240
AVGVVTGTKI RELVEKIAAA YHVKIVPGSS VRRIRRFLAG QHDIVLERDY KGVLWEVEGE
250 260 270 280 290 300
EERALHAVKL AESEAKQEST EGAVCLYEQH IEEEENFTVE AGEAYQVDIQ MAAAPQKGAI
310 320 330 340 350 360
RLYDFQGYDE SGTVINQYGR DFSVTYGLKI QASRKLLSQL EATTSVYPFK LSHVESNVAK
370 380 390 400 410 420
ARLGLGEILA HQILVPIPVK VAKFVPLAAL YEFSKNSKAR ARDEASKAVP VARNSSSVLL
430 440 450 460 470 480
TNDACLRLTG GQAFPPPYVH SAFELPEDVT NLLKLVGHKH GAKVKDVLPG DVDMAPAKEA
KMEE