Q6CAR6

PR
Gene name
SYF1 (YALI0D00561g)
Protein name
Pre-mRNA-splicing factor SYF1
Names
Species
Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica)
KEGG Pathway
yli:YALI0D00561g
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

671-736 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q6CAR6

Entry ID Method Resolution Chain Position Source
AF-Q6CAR6-F1 Predicted AlphaFoldDB

No variants for Q6CAR6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q6CAR6

No associated diseases with Q6CAR6

10 regional properties for Q6CAR6

Type Name Position InterPro Accession
repeat HAT (Half-A-TPR) repeat 30 - 62 IPR003107-1
repeat HAT (Half-A-TPR) repeat 74 - 106 IPR003107-2
repeat HAT (Half-A-TPR) repeat 246 - 281 IPR003107-3
repeat HAT (Half-A-TPR) repeat 373 - 409 IPR003107-4
repeat HAT (Half-A-TPR) repeat 411 - 460 IPR003107-5
repeat HAT (Half-A-TPR) repeat 462 - 494 IPR003107-6
repeat HAT (Half-A-TPR) repeat 496 - 529 IPR003107-7
repeat HAT (Half-A-TPR) repeat 531 - 563 IPR003107-8
repeat HAT (Half-A-TPR) repeat 598 - 632 IPR003107-9
repeat HAT (Half-A-TPR) repeat 634 - 667 IPR003107-10

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
post-mRNA release spliceosomal complex A spliceosomal complex that is formed following the release of the spliced product from the post-spliceosomal complex and contains the excised intron and three snRNPs, including U5.
Prp19 complex A protein complex consisting of Prp19 and associated proteins that is involved in the transition from the precatalytic spliceosome to the activated form that catalyzes step 1 of splicing, and which remains associated with the spliceosome through the second catalytic step. It is widely conserved, found in both yeast and mammals, though the exact composition varies. In S. cerevisiae, it contains Prp19p, Ntc20p, Snt309p, Isy1p, Syf2p, Cwc2p, Prp46p, Clf1p, Cef1p, and Syf1p.
U2-type catalytic step 2 spliceosome A spliceosomal complex that contains the U2, U5 and U6 snRNPs bound to a splicing intermediate in which the first catalytic cleavage of the 5' splice site has occurred. The precise subunit composition differs significantly from that of the catalytic step 1, or activated, spliceosome, and includes many proteins in addition to those found in the U2, U5 and U6 snRNPs.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

2 GO annotations of biological process

Name Definition
generation of catalytic spliceosome for first transesterification step Formation of a catalytic spliceosome complex ready to perform the first splicing reaction. This occurs by an ATP-dependent conformational change of the pre-catalytic spliceosome.
mRNA splicing, via spliceosome The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSQHELDIAS SPGDVRPWIR YISSVKNDKT TARQKCILFE RAVTALPRSY KLWKEYLDFR
70 80 90 100 110 120
SGLCTGLNPI KHADEYDRVN ALYEKSLVLL HKMPVIWLQY LQFLMLQPKV TKTRSVINEA
130 140 150 160 170 180
LRSLPVQQHP RVLKLALQFG TKVGGPTSVQ IWKRYVLAYP DQKETMAQSL IKMGYHGEAA
190 200 210 220 230 240
VVLIELLNAS GDNYALWTEL VDLIGESDKL TLEPPVEQII SSGIKRFPDQ RGPLTVQLAN
250 260 270 280 290 300
FLVRNGDLES ARDVFEDGIT TANTVRDFTV VFDAYAEFEE RIVTHLIENE SPMADLRIAK
310 320 330 340 350 360
LDHLLERRPF LISDVRLRRE PYSVLEWQKR IALYEDPAET VAAYTEAVQS IPPAKADGKL
370 380 390 400 410 420
SQLWISWAKF YAEDRETACE IYHKATLVPY KSVSELADVY LAWSQYESEN DHWENAVKII
430 440 450 460 470 480
KQALESPNTH VSYHNSDLTA QDRIHKSVRL WSYYADLVES YGTFEETKQV YEKIMALDLL
490 500 510 520 530 540
TPLFVVNYAT LLEENDHFEE MFKVYEKGIS LFEESAFEIW NLYLVKASPR LGLERLRDLF
550 560 570 580 590 600
EDAISKFPTQ KALYILYGKL EEDRGLVRNA MRVYSAMCDH VKTSETFKYY IGRTVENFGL
610 620 630 640 650 660
AATRPVYDKA LESLPNKDAS ELALDYAQME EKLGEIDRAR AIYGYGSQFS DPQIIKYYDA
670 680 690 700 710 720
WHKFEVAHGT EDTFKDMLRI KRSIQAQFNT DIHYATTAAE VKKGTVQEFV KGETVQKGNI
730
EPPVAQANED EIELDI