Q6CAB8
Gene name |
GPI10 (YALI0D04202g) |
Protein name |
GPI mannosyltransferase 3 |
Names |
GPI mannosyltransferase III, GPI-MT-III, Glycosylphosphatidylinositol-anchor biosynthesis protein 10 |
Species |
Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica) |
KEGG Pathway |
yli:YALI0D04202g |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q6CAB8
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q6CAB8-F1 | Predicted | AlphaFoldDB |
No variants for Q6CAB8
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q6CAB8 | |||||
No associated diseases with Q6CAB8
No regional properties for Q6CAB8
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q6CAB8 | |||
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| endoplasmic reticulum membrane | The lipid bilayer surrounding the endoplasmic reticulum. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| alpha-1,2-mannosyltransferase activity | Catalysis of the transfer of a mannose residue to an oligosaccharide, forming an alpha-(1->2) linkage. |
| glycolipid mannosyltransferase activity | Catalysis of the transfer of an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-D-mannosyl-D-mannose linkage. |
| mannosyltransferase activity | Catalysis of the transfer of a mannosyl group to an acceptor molecule, typically another carbohydrate or a lipid. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| GPI anchor biosynthetic process | The chemical reactions and pathways resulting in the formation of a glycosylphosphatidylinositol (GPI) anchor that attaches some membrane proteins to the lipid bilayer of the cell membrane. The phosphatidylinositol group is linked via the C-6 hydroxyl residue of inositol to a carbohydrate chain which is itself linked to the protein via an ethanolamine phosphate group, its amino group forming an amide linkage with the C-terminal carboxyl of the protein. Some GPI anchors have variants on this canonical linkage. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MMQHKEIKHP | YQGIKYTVLV | VIAAFRVANA | LTTKTFFQPD | EYWQSLEPAH | RLAYGYGYLT |
| 70 | 80 | 90 | 100 | 110 | 120 |
| WEWHEGLRSS | LPPLVGAGIY | KALQLLGLDD | PRIVRIAPKI | VMALFASAGD | VYTWKLSARL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| QGPAEAPWAL | FVSLLSAFNW | FFLTRTFSNS | AEMVLTAVAL | NYWSFNGKEV | NFKRLSVALF |
| 190 | 200 | 210 | 220 | 230 | 240 |
| IGAISCVLRP | TNAILWAVLG | LHLVLTTTAK | MRVLWLAVRN | VALVFAATYY | IDYLYYGEPV |
| 250 | 260 | 270 | 280 | 290 | 300 |
| FPLLNFLKFN | LLQSLAHFYG | TSPTLYYFYE | ALPLLTVGWL | PLTLWGLWIN | RSQVLVKAAL |
| 310 | 320 | 330 | 340 | 350 | 360 |
| AVVVAFSLIR | HKEVRFIYPL | VPILHMAAAE | AITQTPKKLR | KWLVWSLALV | NILVAGYFSQ |
| 370 | 380 | 390 | 400 | 410 | 420 |
| VHQRGVVDVV | EYLSTEPQVT | SVGFLMPCHS | TPYQSHLHRD | IPVWFLTCEP | PIGFTAEEQM |
| 430 | 440 | 450 | 460 | 470 | 480 |
| TYRDQADQFY | DDPLQFVQTQ | FPESVAVSAR | EARTPLFHPS | HLAIFESLEK | KSPEVIEHLV |
| 490 | 500 | ||||
| ELGYKRGKTF | FNSHFHDDWR | REGDVVVYNL |