Q6C9N2
Gene name |
SFH1 (YALI0D09779g) |
Protein name |
Chromatin structure-remodeling complex subunit SFH1 |
Names |
RSC complex subunit SFH1, SNF5 homolog 1 |
Species |
Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica) |
KEGG Pathway |
yli:YALI0D09779g |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q6C9N2
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q6C9N2-F1 | Predicted | AlphaFoldDB |
No variants for Q6C9N2
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q6C9N2 | |||||
No associated diseases with Q6C9N2
No regional properties for Q6C9N2
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q6C9N2 | |||
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| nuclear chromosome | A chromosome that encodes the nuclear genome and is found in the nucleus of a eukaryotic cell during the cell cycle phases when the nucleus is intact. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
| RSC-type complex | A SWI/SNF-type complex that contains a bromodomain containing-protein, such as yeast Rsc1 or Rsc4 or mammalian PB1/BAF180. The RSC complex is generally recruited to RNA polymerase III promoters and is specifically recruited to RNA polymerase II promoters by transcriptional activators and repressors; it is also involved in non-homologous end joining. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| transcription coregulator activity | A transcription regulator activity that modulates the transcription of specific gene sets via binding to a DNA-bound DNA-binding transcription factor, either on its own or as part of a complex. Coregulators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second class remodels the conformation of chromatin in an ATP-dependent fashion. A third class modulates interactions of DNA-bound DNA-binding transcription factors with other transcription coregulators. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| cell cycle | The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division. |
| chromatin remodeling | A dynamic process of chromatin reorganization resulting in changes to chromatin structure. These changes allow DNA metabolic processes such as transcriptional regulation, DNA recombination, DNA repair, and DNA replication. |
| regulation of transcription by RNA polymerase II | Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MGEKPNRIGR | ANISYINHDH | IFLPSFQPSY | PSRQLHPLIS | SQNKVHSSIV | HLPKVASPSS |
| 70 | 80 | 90 | 100 | 110 | 120 |
| PETQQHSQAP | LFITHIMSGL | PQALASGFAA | RVREGGTTLY | INTTPMLRSA | RHNTAVNYAE |
| 130 | 140 | 150 | 160 | 170 | 180 |
| FEEDFDANDF | EDDDDDDQSQ | RESRDGSEEA | EGDEDGTKKE | EQDKFAGLKA | PLVSNEPKRA |
| 190 | 200 | 210 | 220 | 230 | 240 |
| APPVRPVMYP | QEVLEELSQV | KEPTLIPIRV | AVENIDVFRV | QDFFLWDADE | KILTPEQFAT |
| 250 | 260 | 270 | 280 | 290 | 300 |
| LTCADLDVPI | GYSAQMSAQI | KKQLAEYTAA | PALPKDVEVH | VIVELAVTVD | KIVYEDKFEW |
| 310 | 320 | 330 | 340 | 350 | 360 |
| DLSGEYATPQ | EFARTVVQDL | GLGQEFYPAI | TYQLYETLGK | LQKAWLERSI | PLDVDNRAAF |
| 370 | 380 | 390 | 400 | 410 | 420 |
| GLEAGLRVDQ | DNLGESWVPR | VEEMTPEEMQ | KREMERDRSS | RRLKRESARM | AEVPYVDLDS |
| 430 | 440 | ||||
| LYSRKRRRRF | DEDSRSGSPM | W |