Q6C997
Gene name |
PPM1 (YALI0D12881g) |
Protein name |
Leucine carboxyl methyltransferase 1 |
Names |
Protein phosphatase methyltransferase 1, [Phosphatase 2A protein]-leucine-carboxy methyltransferase 1 |
Species |
Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica) |
KEGG Pathway |
yli:YALI0D12881g |
EC number |
2.1.1.233: Methyltransferases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q6C997
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q6C997-F1 | Predicted | AlphaFoldDB |
No variants for Q6C997
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q6C997 | |||||
No associated diseases with Q6C997
No regional properties for Q6C997
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q6C997 | |||
Functions
| Description | ||
|---|---|---|
| EC Number | 2.1.1.233 | Methyltransferases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| protein C-terminal leucine carboxyl O-methyltransferase activity | Catalysis of the reaction: S-adenosyl-L-methionine + protein L-leucine = S-adenosyl-L-homocysteine + protein L-leucine methyl ester. This modification occurs only at the oxygen atoms of the free alpha carboxyl group of a leucine residue at the C-terminus of the protein. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| C-terminal protein methylation | The methylation of the C-terminal amino acid of a protein. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MNLRKDKVVQ | STDGDALSSK | YSAVQKGYLQ | DEFIDLFVAG | SKQAAAQQGP | GSARKVVAQF |
| 70 | 80 | 90 | 100 | 110 | 120 |
| QPKLPLINRG | TFVRHHAIDV | LVDRFLAAKK | PGQRVQIISL | GAGSDTRPFS | LWSSKPENRD |
| 130 | 140 | 150 | 160 | 170 | 180 |
| EILYHEIDFA | VSVERKRDII | MQDSTLRELV | GAQEYDKTTG | MHTQRYHLHG | IDLRSIGPGF |
| 190 | 200 | 210 | 220 | 230 | 240 |
| VLPGSDPSLA | TLIISECCLC | YLEPDQAKQV | IFWITSEFTN | STIVMYEPLS | GQDQFGQVMI |
| 250 | 260 | 270 | 280 | 290 | 300 |
| ENLASRGISI | PSMTKFPSLE | SQIERFKAAG | YTEVLATSMD | VIHDEWLSPE | EQQRIHGLEF |
| 310 | 320 | ||||
| LDEREELLLL | LKHYCVVWAS | NLTK |