Q6C7X8

PR
Gene name
DBP10 (YALI0D24497g)
Protein name
ATP-dependent RNA helicase DBP10
Names
Species
Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica)
KEGG Pathway
yli:YALI0D24497g
EC number
3.6.4.13: Acting on ATP; involved in cellular and subcellular movement
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-133 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q6C7X8

Entry ID Method Resolution Chain Position Source
AF-Q6C7X8-F1 Predicted AlphaFoldDB

No variants for Q6C7X8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q6C7X8

No associated diseases with Q6C7X8

6 regional properties for Q6C7X8

Type Name Position InterPro Accession
domain Helicase, C-terminal 370 - 529 IPR001650
domain DEAD/DEAH box helicase domain 126 - 291 IPR011545
domain DBP10, C-terminal 756 - 815 IPR012541
domain Helicase superfamily 1/2, ATP-binding domain 121 - 322 IPR014001
domain RNA helicase, DEAD-box type, Q motif 102 - 130 IPR014014
domain DDX54/DBP10 family, DEAD-box helicase domain 102 - 306 IPR033517

Functions

Description
EC Number 3.6.4.13 Acting on ATP; involved in cellular and subcellular movement
Subcellular Localization
  • Nucleus, nucleolus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleolus A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.

4 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP hydrolysis activity Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.
RNA binding Binding to an RNA molecule or a portion thereof.
RNA helicase activity Unwinding of an RNA helix, driven by ATP hydrolysis.

1 GO annotations of biological process

Name Definition
rRNA processing Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSDSEVEYDI AGSLNPGVDS EDDYSSGSES DSEIPDIIED SEDETGPQQG EPGTMTFPNL
70 80 90 100 110 120
ELSDDDDDDD DDDEGRKKKK KKTDDSVESY FGAPQTGKKS SGSFAGLGLS QLVLKNIARK
130 140 150 160 170 180
GFKQPTPIQR KTIPLVLEGK DVVGMARTGS GKTAAFVLPM LEKLKVHSAK VGARAVILSP
190 200 210 220 230 240
SRELALQTLK VVKDFSAGTD LRLAMLVGGD SLEEQFKMMM SNPDIIIATP GRFLHLKVEM
250 260 270 280 290 300
ELSLASVEYI CFDEADRLFE LGFGEQMNEL LASLPSNRQT LLFSATLPKT LVEFAKAGLH
310 320 330 340 350 360
DPILVRLDAE TKLPEHLEMT FFAVKENQRD ACLAFILKEV IQMPFATPEQ LKELERLDER
370 380 390 400 410 420
AIDDGERDED RKQKRPKFKK ERLPPAHQLP SEKSTIVFCP TKHHVEYVIV LLQTLGYAVS
430 440 450 460 470 480
YIYGTLDQHA RKNQLYRFRT GKTSILVVTD VAARGIDVPV LANVINYSLP PSPKVFIHRV
490 500 510 520 530 540
GRTARAGNRG WAYSIIKDND IPYLLDLEVF LGRKLLTPRL FKQQNPDPSA EPDYVNTLTI
550 560 570 580 590 600
GAPPRQALEI HGEELAQMVK DSYELQQLSE VAVKGERMYN KTKGSASQES AKRSKQIMAL
610 620 630 640 650 660
GWDDHHLMFG EDGESAKDAL LARLGQKRIR ETVFEFRKSK TTSGAEMMAT RRAQLAPIQR
670 680 690 700 710 720
RAAEKRAIQE KERLAGLVHS QDAEIARSTE EDMATEADLT GFTTEEDLRA AKKAQKSKKR
730 740 750 760 770 780
SFRDSENFMS HYAPTNDDKG YAVGNFAGAA SNATFDLIND GSEMQQKQGM KWDKKKGKFI
790 800 810 820 830 840
NAGSEGGKKF IRGEGGQRIA ASFRSGRFDK WKAAHKVGNL KVGALEESGP ATKRVLSARE
850 860 870 880 890 900
FKHNKNEAPK RADKYRDDFH KQKTKVAAAK EDGRIQKPQP KSELKSTADV RKSRILAEKR
910 920
KQKNARPSRG GRGGGRGGRG GGRGGR